Meningococcal infection in the Russian Federation: a ten-year follow-up


DOI: https://dx.doi.org/10.18565/epidem.2022.12.2.6-11

Koroleva M.A., Gritsay M.I., Koroleva I.S., Melnikova A.A.

1) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 2) Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
The data accumulated during a long follow-up period could determine the rate, trends, and structure of morbidity, mortality, and death in invasive meningococcal disease (IMD) in the Russian Federation (RF).
Objective. To analyze the epidemiological features of IMD in the RF during a 10-year follow-up period.
Materials and methods. The personalized information on 10,119 cases of IMD, which had been obtained by the Russian Reference Center for Monitoring Bacterial Meningitis (RCMBM) in 2010-2019, was retrospectively analyzed.
Results. The incidence of IMD in the RF tends to decrease. However, since 2016 there has been a rise in the incidence of IMD with an average annual increase of 10.4% and an absolute increase of 0.15 per 100,000 population; the involvement of adolescents and young adults in the epidemic process (a rise in the 2016–2019 incidence by 2.4 and 2.6 times, respectively); a 5.5-fold increase in the number of cases caused by serogroup A meningococcal strains. The highest morbidity and mortality rates were found among the children, but the role of adults was significant in the structure of morbidity and mortality for IMD.
Conclusion. The investigation has established the precursors of epidemiological troubles in relation to IMD, indicating a possible threat of the next periodic rise in its incidence. The findings could optimize MD vaccination in the RF and increase its coverage among the population

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Koroleva M.A., Gritsay M.I., Mironov K.O., Yarygina E.A., Valdokhina A.V., Yanushevich Yu.V. et al. [Epidemiological manifestations of an outbreak of meningococcal infection caused by serogroup A Neisseria meningitidis in Novosibirsk in 2019]. Epidemiology and infectious diseases. Current items 2021; 11(2): 13–21. (In Russ.). DOI: 10.18565/epidem. 2021.11.2.13-21


About the Autors


Maria A. Koroleva, Cand. Med. Sci., Senior Researcher, Laboratory for Epidemiology of Meningococcal Disease and Purulent Bacterial Meningitides, , Central Research Institute of Epidemiology. Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; korolevamaria389@mail.ru; http://orcid.org/0000-0002-2714-1191
Maria I. Gritsay, Postgraduate Student, Laboratory for Epidemiology of Meningococcal Disease and Purulent Bacterial Meningitides, Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being, Moscow, Russia; maria-griz@mail.ru
Irina S. Koroleva, МD, Нead, Laboratory for Epidemiology of Meningococcal Infection and Purulent Bacterial Meningitis, Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being, Moscow, Russia;. korol@yandex.ru; http://orcid.org/0000-0003-0578- 146X
Albina A. Melnikova, Cand. Med. Sci., Deputy Head, Epidemiological Surveillance Directorate, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being Moscow, Russia; melnikova_aa@gsen.ru


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