Crimean hemorrhagic fever in a COVID-19 patient: a clinical case


DOI: https://dx.doi.org/10.18565/epidem.2022.12.4.68-71

Abuova G.N., Pshenichnaya N.Yu., Berdalieva F.A., Polukchi Т.V., Aliev D.S., Sadykhova D.К., Aliev E.Yu., Lizinfeld I.A., Akimkin V.G.

1) South Kazakhstan Medical Academy, Shymkent, Kazakhstan; 2) Central Research Institute of Epidemiology, Moscow, Russia; 3) Shymkent City Infectious Diseases Hospital, Shymkent, Kazakhstan
Crimean hemorrhagic fever (CHF) is endemic in the southern regions of the Republic of Kazakhstan. During the COVID-19 pandemic, there are cases of CHF and COVID-19 coinfection, presenting substantial difficulties in both the diagnosis and treatment of these patients. CHF cases and outbreaks are an additional threat during the pandemic due to the severity of the course, the difficulty of differential diagnosis, and the poor prognosis of CHF and COVID- 19. The 2020–2021 summer as the most active season for the incidence of CHF in the city of Shymkent and the Turkestan Region coincided with the peaks in the waves of the COVID-19 pandemic, whereas the similarity of the symptoms of the diseases involved difficulties in establishing a diagnosis.
The paper describes clinical case of a patient with severe CHF in the presence of clinical signs of coronavirus infection, COVID-19-associated pneumonia, with a favorable outcome, who has been treated in the Shymkent City Infectious Diseases Hospital. Timely diagnosis and etiotropic therapy with ribavirin, replacement treatment with blood drugs and the use of immunized convalescent plasma could achieve a favorable outcome.
Keywords: hemorrhagic syndrome, pandemic, COVID-19, coagulopathy, Crimean hemorrhagic fever, thrombocytopenia, intoxication
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About the Autors

Professor Guldzhan N. Abuova, Can. Med. Sci., Head, Department of Infectious Diseases and Dermatovenerology, South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan; dr.abuova@gmail.com; http://orcid.org/ 0000-0002-1210-2018
Professor Natalia Yu. Pshenichnaya, MD, Deputy Director for Clinical and Analytical Work, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Moscow, Russia; natalia-pshenichnaya@yandex.ru; http://orcid.org/0000-0003-2570-711X
Farida A. Berdalieva, Can. Med. Sci., Associate Professor, Department of Infectious Diseases and Dermatovenerology, South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan; fberdalieva@mail.ru; https://orcid.org/0000-0001-9680-1678
Tatiana V. Polukchi, Assistant Lecturer, Department of Infectious Diseases and Dermatovenerology, South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan; tatyana_polukchi@mail.ru; https://orcid.org/0000-0002-6134-884X
Daulet S. Aliev, Assistant Lecturer, Department of Infectious Diseases and Dermatovenerology, South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan; dauletaliev68@mail.ru; https://orcid.org/0000-0003-1006-4473
Dana K. Sadykhova, Assistant Lecturer, Department of Infectious Diseases and Dermatovenerology, South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan; danoka.kz@mail.ru; https://orcid.org/0000-0002-3218-6204
Eldar Yu. Aliev, Highest-Category Resuscitator, Shymkenr City Infectious Diseases Hospital, Shymkent, Republic of Kazakhstan; eldar_aliev_84@inbox.ru
Irina A. Lizinfeld, Advisor, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; irinalizinfeld@gmail.com; https://orcid.org/0000-0002-8114-1002
Professor Vasily G. Akimkin, Academician of the Russian Academy of Sciences, MD, Director, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; crie@pcr.ru; http://orcid.org/0000-0003-4228-9044


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