Epi­demiological characteristics of acute infections with concomitant respiratory and digestive tract lesions in children

DOI: https://dx.doi.org/10.18565/epidem.2019.9.2.24-30

Kanner E.V., Pechkurov D.V., Gorelov A.V.

1) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 2) Samara State Medical University, Ministry of Health of Russia, Samara, Russia; 3) I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia
Objective. To provide the current epidemiological characteristics of acute infections of the respiratory and digestive tracts in children, as well as those of infections occurring with a concomitant lesion of both systems.
Subjects and methods. Case histories were analyzed in 4842 children aged 3 months to 14 years who were admitted to Moscow infectious diseases hospitals. The diagnosis of acute respiratory and intestinal infections and their etiology were established on the basis of clinical presentations and laboratory findings (according to the results of bacteriological, virological and immunological studies).
Results. There was an isolated respiratory tract lesion in 2518 (52.01%) children, an isolated digestive tract lesion in 930 (19.20%), and concomitant respiratory and digestive tract lesions (CRDTL) in 1394 (28.79%). The problem of acute infections concurrent with CRDTL is most urgent for younger age groups. The investigators identified four variants of relationships between the symptoms of respiratory and digestive tract lesions, the most frequent one of which is the primary manifestation of respiratory symptoms and early (within 48 hours) addition of intestinal syndrome. Mixed infection was detected in 54% of cases of concomitant respiratory and intestinal symptoms. The most frequent causative agent of infections with CRDTL was rotavirus (53%). Rotavirus was the most common causative agent of infections concurrent with CRDTL (53%).
Conclusion. Acute infections concurrent with CRDTL are an urgent problem of pediatrics and require the elaboration of new approaches to diagnosing, preventing, and treating these conditions.


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About the Autors

Ekaterina V. Kanner, Cand. Med. Sci., Senior Researcher, Clinical Department of Infectious Diseases, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; e-mail: crie@pcr.ru
Prof. Dmitriy V. Pechkurov, MD, Head, Department of Children’s Diseases, Samara State Medical University, Ministry of Health of Russia, Samara, Russia; e-mail: kdbsamgmu@yandex.ru; ORCID: http://orcid.org/0000-0002-5869-2893
Prof. Alexandr V. Gorelov, MD, Corresponding Member of the Russian Academy of Sciences; Deputy Director for Scientific Work, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Professor, Department of Children’s Diseases, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of  Health of Russia,  Moscow, Russia; е-mail: crie@pcr.ru; Scopus Author ID: 56848123300; ORCID: http://orcid.org/0000-0001-9257-0171

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