Русский
Clinical and epidemiological features of staphylococcal enterocolitis in infants: a retrospective study
DOI: https://dx.doi.org/10.18565/epidem.2023.13.4.78-83
Kimirilova O.G., Kharchenko G.A.
Astrakhan State Medical University of the Ministry of Health of Russia, Astrakhan, Russia
Materials and methods. Based on a study of 198 case histories of patients under the age of 1 year treated at the Regional Infectious Diseases Clinical Hospital named after A.M. Nichoga (Astrakhan) from January 2017 to December 2021, the duration of the main symptoms of SE (fever, diarrhea, toxicosis with dehydration, the frequency of intestinal dysbiosis and secondary lactase deficiency) was analyzed.
Results. The age structure of patients with SE was dominated by children under 6 months of age (68%). 57% of children had a history of prematurity, omphalitis, purulent conjunctivitis, etc., and 86% of children were on formula and mixed feeding. The food route of infection was identified in 78% of children. In 62% of patients, the disease was moderate. Among the lesions of the gastrointestinal tract, enterocolitis and gastroenterocolitis accounted for 79%, colitis and hemocolitis – 14%, enteritis – 7%, dehydration – 16%, intestinal dysbiosis - 44%, secondary lactase deficiency – 48%. A direct correlation between late hospitalization of patients (3 days after the onset of the disease) and the presence of dehydration was established (r = 0.72; p < 0.001).
Conclusion. Intestinal staphylococcal infection in infants most often occurred in the form of primary SE (70%) with a predominance of moderate forms (62%) and the development of secondary lactase deficiency (48%). The duration of the disease, fever, diarrhea syndrome, and repeated isolation of staphylococcus in patients with secondary SE is higher than in primary ones.
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About the Autors
Olga G. Kimirilova, Сand. Мed. Sci., Associate Professor, Department of Childhood Infections, Astrakhan State Medical University, Astrakhan, Russia; 0lgakim@mail.ru; http://orcid.org/0000-0003-4066-2431
Professor Gennady A. Kharchenko, MD, Head, Department of Childhood Infections, Astrakhan State Medical University, Astrakhan, Russia: Xarchenkoga@mail.ru; http://orcid.org/0000-0001-7764-0995.
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