Русский
Epidemiological characteristics of concomitant diseases (tuberculosis and parenteral viral hepatitides) among the population of Moscow
DOI: https://dx.doi.org/10.18565/epidem.2019.9.2.18-23
Solovyev D.V., Smirnova O.A., Asratyan A.A.
1) Center of Hygiene and Epidemiology in the City of Moscow, Moscow, Russia; 2) Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia, Moscow, Russia; 3) I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia
Materials and methods. Data on concurrent PVH + TB diseases were obtained on the basis of an analysis of 276 574 infectious disease registration cards available in the Moscow Citywide Automatic Information System «ORUIB» for registering the cases of infectious and parasitic diseases and the statistical data of the Center of Hygiene and Epidemiology in the City of Moscow. Epidemiological and statistical methods were used.
Results. The number of patients with the concomitant forms ranged from 311 to 406 cases annually (the incidence rate was 3 to 3.7 0/0000), while every ten patients with TB were infected with parenteral hepatitis viruses. These patients were more often found to have severe forms of TB: generalized TB and disseminated TB were by 5.8 and 2.6 times, respectively. The main cause of death was TB (60 to 80% of cases). The risk for a fatal outcome was significantly higher (by 32.0%) in the group of patients with TB burdened by PVH. The chronic forms of hepatitis B and C in patients with TB were significantly more common (by 39 and 116 times, respectively) than among the total population (p <0.05). The incidence of all clinical forms of PVH in patients with TB was 46 times higher than that among the total population (the correlation coefficient was 0.87).
Conclusion. Every ten patients with TB were infected with PVH viruses. The severe forms of TB can contribute to the long-term release of mycobacteria into the environment and increase the number of sources of infection. The modern features of the epidemic situation of concomitant incidence of PVH + TB were revealed in the population of Moscow in the period 2009 to 2017.
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About the Autors
Dmitry V. Solovуev, Cand. Med. Sci., Head, Antiepidemic Department, Center of Hygiene and Epidemiology in the City of Moscow, Moscow, Russia; е-mail: dv_soloviev@list.ru; ORCID: http://orcid.org/0000-0002-2133-3475
Olga A. Smirnova, Epidemiologist, Antiepidemic Department, Centre of Hygiene and Epidemiology in the City of Moscow, Moscow, Russia; е-mail: incandessence19@rambler.ru; ORCID: http://orcid.org/0000-0002-3058-6538
Prof. Аrpik A. Asratyan, MD, Leading Researcher, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; Professor, Department of Epidemiology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia; e-mail: zasratyan@yahoo.com; ORCID: https://orcid.org/0000-0003-1288-7561
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