Modern approaches to assessment and correction of cardiovascular risks in people living with HIV


DOI: https://dx.doi.org/10.18565/epidem.2024.14.3.42-8

Shilov A.M., Popova A.A., Pokrovskaya A.V.

1) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 2) Patrice Lumumba Peoples› Friendship University of Russia, Moscow, Russia; 3) Russian Medical Academy of Continuous Professional Education, Moscow, Russia
Objective. Review of methods for calculating the risks of cardiovascular events in people living with HIV (PLHIV), recommended by various organizations for the prevention and control of HIV infection. Study of the role of SCORE2 and SCORE2-OP scales in assessing cardiovascular risk within the framework of follow-up care of PLHIV.
Materials and methods. The methods for calculating the risks of fatal and non-fatal cardiovascular events in PLHIV recommended by Russian and foreign organizations for the prevention and control of HIV infection were analyzed. The calculation of cardiovascular risks using the SCORE2 and SCORE2-OP systems was carried out based on data obtained during the follow-up care of 240 patients in the period from 2022 to 2023.
Results. It was revealed that the studied recommendations do not include systems for calculating cardiovascular risks developed specifically for PLHIV. All recommended assessment scales can potentially underestimate the real risks of cardiovascular events in PLHIV. The use of the SCORE2 and SCORE2-OP scales within the cohort of PLHIV revealed a significant predominance of individuals with high and very high cardiovascular risk in all age groups compared to those in the general population.
Conclusion. The lack of specific tools for stratification of cardiovascular risks in PLHIV requires further study of existing assessment systems for their effectiveness. Increased risks of cardiovascular events in PLHIV determine the need for active use of assessment scales as part of their follow-up care.

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About the Autors


Andrey M. Shilov, Postgraduate Student, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Teaching Assistant at the Department of Infectious Diseases with Courses in Epidemiology and Phthisiology, Medical Institute, Patrice Lumumba Peoples’ Friendship University of Russia, Moscow, Russia; sh_andrey_max@mail.ru; https://orcid.org/0009-0000-7966-9708
Anna A. Popova, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Associate Professor at the Department of Infectious Diseases, Russian Medical Academy of Continuous Professional Education, Moscow, Russia; popova@cmd.su; https://orcid.org/0000-0001-9484-5917
Anastasia V. Pokrovskaya, МD, Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Associate Professor, Department of Infectious Diseases with Courses in Epidemiology and Phthisiology, Medical Institute, Patrice Lumumba Peoples’ Friendship University of Russia, Moscow, Russia; pokrovskaya@cmd.su; https://orcid.org/0000-0002-2677-0404


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