Clustering of standardized cumulative incidence rates over a multi-year period as a method for analyzing the spatial distribution of disease cases


DOI: https://dx.doi.org/10.18565/epidem.2024.14.1.31-5

Dubodelov D.V., Ugleva S.V., Gasanov G.A., Korabelnikova M.I., Sycheva N.V., Zavolozhin V.A., Esman A.S., Vlasenko N.V., Semenenko T.A., Kuzin S.N., Akimkin V.G.

1) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 2) N.F. Gamaleya National Research Center for Epidemiology and Microbiology of the Ministry of Health of Russia, Moscow, Russia
Objective. Rationale for the use of visualization of the results of hierarchical clustering of standardized indicators of cumulative incidence over a long-term period as a method for analyzing the spatial distribution of disease cases.
Materials and methods. Information on the incidence of chronic hepatitis B (CHB) in the population of 85 constituent entities of the Russian Federation for the period from 2014 to 2022 was analyzed according to statistical form No. 2 Information on infectious and parasitic diseases. All calculations were performed using Python libraries.
Results. The sequence of actions for obtaining and interpreting the results of hierarchical clustering of indicators of long-term cumulative incidence in the constituent entities of the Russian Federation is described in order to analyze the long-term incidence of CHB in the population.
Conclusion. The proposed method significantly increases the information content and objectivity of the results of studying the spatial distribution of CHB cases.

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About the Autors


Dmitry V. Dubodelov, Cand. Med. Sci., Senior Researcher, Laboratory of Viral Hepatitis, Department of Molecular Diagnostics and Epidemiology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; dubodelov@cmd.su; https://orcid.org/0000-0003-3093-5731
Svetlana V. Ugleva, МD, Scientific Consultant, Organizational and Methodological Department, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; ugleva@cmd.su; https://orcid.org/0000-0002-1322-0155
Gasan A. Gasanov, Post-graduate Student, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; gasanov@cmd.su; https://orcid.org/0000-0002-0121-521X
Marina I. Korabel’nikova, Researcher, Laboratory of Viral Hepatitis, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; korabelnikova@cmd.su; https://orcid.org/0000-0002-2575-8569
Natalya V. Sycheva, Junior Researcher, Laboratory of Health Care Associated Infections, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia;, natsy@bk.ru, http://orcid.org/0000-0001-8557-6540
Vasily A. Zavolozhin, Junior Researcher, Laboratory of Viral Hepatitis, Department of Molecular Diagnostics and Epidemiology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; Zavolozhin@cmd.su; https://orcid.org/0000-0003-4015-1105
Anna S. Esman, Researcher, Laboratory of Molecular Methods for Genetic Polymorphisms Research, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; esman@cmd.su; https://orcid.org/0000-0002-5456-7649
Natalia V. Vlasenko, Researcher, Laboratory of viral hepatitis, Department of molecular diagnostics and epidemiology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; vlasenko@cmd.su; https://orcid.org/0000-0002-2388-1483
Professor Tatiana A. Semenenko, MD, Head, Epidemiology Department, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of Russia, Moscow, Russia; semenenko@gamaleya.org; https://orcid.org/0000-0002-6686-9011
Professor Vasily G. Akimkin, Academician of the Russian Academy of Sciences, MD. Director, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; vgakimkin@yandex.ru; https://orcid. org/0000-0003-4228-9044


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