Русский
Cardiovascular disease in HIV infection
DOI: https://dx.doi.org/10.18565/epidem.2023.13.1.55-9
Tuaeva R.G., Loseva O.K., Mazus A.I., Nagibina M.V., Bessarab T.P., Vengerov Yu.Ya.
1) Moscow Research and Practical Center for Dermatovenereology and Cosmetology, Moscow City Healthcare Department, Moscow, Russia; 2) Moscow City Center for AIDS Prevention and Control, Moscow City Healthcare Department, Moscow, Russia; Moscow, Russia; 3) A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia
Subjects and methods. Fifty patients (37 men and 13 women) were examined. 78% of them were aged 30 to 50 years. Fourteen patients were found to have Stage 3 (latent) HIV infection; 36 had Stage 4 (secondary diseases). The authors analyzed medical records, age, gender, the data of physical examination and laboratory studies, comorbidities, the results of electrocardiography, echocardiography, Doppler ultrasound of the brachiocephalic arteries, assisted reproductive technology (ART) regimens, and disease outcomes.
Results. Cardiac disease (CD) was detected in 29 (58%) patients. Tricuspid valve infective endocarditis (65.5%) was diagnosed more often than others. Comparing with the patients receiving ART showed that 14 of the 21 patients who did not have ART were found to have the disease. Three of the patients who received ART timely and regularly were diagnosed with CD.
Conclusion. CD was detected in half of the patients with Stage 3 HIV infection and in 61% of those with Stage 4. CD occurred in both the patients who did not receive ART and in those who had ART regularly.
Literature
1. French A.L., Gawel S.H., Hershow R., Benning L., Hessol N.A., Levine A.M. et al. Trends in mortality and causes of death among women with HIV in the United States: a 10-year study. J. Acquir. Immune Defic. Syndr. 2009; 51(4): 339–406. 2. Knobel H., Jerico C., Montero M. et al. Global cardiovascular risk in patients with HIV infection: concordance and differences in estimates according to three risk equations. Framingham SCORE and PROCAM. AIDS Patient Care. 2007; 21(7): 452–7. 3. Savès M., Chêne G., Ducimetière P., Leport C., Le Moal G. Risk Factors for Coronary Heart Disease in Patients Treated for Human Immunodeficiency Virus Infection Compared with the General Population. Clin. Infect. Dis. 2003; 37(2): 292–8. 4. Klein D., Leyden W., Xu L. Contribution of immunodeficiency to CHD: cohort study of HIV+ and HIV- Kaiser Permanente members. 18th Conference on Retroviruses and Opportunistic Infections. Boston. 2011. Abstract 810. 5. Мудрицкая Т.Н., Турна Э.Ю., Захарова М.А., Григоренко Е.И. Поражение сердечно-сосудистой системы при ВИЧ-инфекции. Крымский терапевтический журнал 2014; (2): 82–8. Mudritskaya T.N., Turna E.Yu., Zakharova M.A., Grigorenko E.I. [Damage to the cardiovascular system in HIV infection]. Crimean therapeutic journal 2014; (2): 82–8. (In Russ.) 6. Якушин С.С., Филиппов Е.В. ВИЧ-инфекция и сердечно-сосудистые осложнения. Клиницист 2011; (2): 6–12. Yakushin S.S., Filippov E.V. [HIV infection and cardiovascular complications]. Clinician 2011; (2): 6–12. (In Russ.). 7. Матиевская Н.В., Токунова И.О., Снежицкий В.А. ВИЧ-инфекция и патология сердечно-сосудистой системы. Медицинские новости. Минск 2015; 249 (6): 6–12. Matievskaya N.V., Tokunova I.O., Snezhitsky V.A. [HIV-infection and pathology of the cardiovascular system]. Medical News. Minsk 2015; 249 (6): 6–12. (In Russ.). 8. Мозгалева Н.В., Пархоменко Ю.Г. Морфофункциональные параллели изменений проводящей системы сердца и рабочего миокарда при инфекционном эндокардите и генерализованном туберкулезе на фоне наркомании и ВИЧ-инфекции. Анналы аритмологии 2017; 14(2): 81–9. Mozgaleva N.V., Parkhomenko Yu.G. [Morphofunctional parallels of changes in the conduction system of the heart and working myocardium in infective endocarditis and generalized tuberculosis in the presence of drug addiction and HIV infection]. Annals of arrhythmology 2017; 14(2): 81–9. (In Russ.).
About the Autors
Renata G. Tuaeva, Dernatovenereologist, Postgraduate Student, Moscow Research and Practical Center for Dermatovenereology and Cosmetology, Moscow City Healthcare Department, Moscow, Russia; 121renata@mail.ru; https://orcid.org/0000-0002-6892-4838
Professor Olga K. Loseva, MD, Moscow Research and Practical Center for Dermatovenereology and Cosmetology, Moscow City Healthcare Department, Moscow, Russia; loseva_ok@mail.ru; https://orcid.org/0000-0002-5033-2746
Aleksey I. Mazus. MD, Honored Health Worker of the Russian Federation; Head, Moscow City Center for AIDS Prevention and Control, Moscow City Healthcare Department, Moscow, Russia; aids@spid.ru; https://orcid.org/0000-0003-2581-1443
Margarita V. Nagibina, MD, Professor, Department of Infectious Diseases and Epidemiology, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia; infektor03@gmail.com; https://orcid.org/0000-0001-5327-9824.
Timur P. Bessarab, Cand. Med. Sci., Head, Department for Prevention of HIV Infection, Moscow City Center for AIDS Prevention and Control, Moscow City Healthcare Department, Moscow, Russia; bessarab@spid.ru; https://orcid.org/0000-0001-6565-7407.
Yuri Ya. Vengerov, MD, Professor, Department of Infectious Diseases and Epidemiology, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia; infektor03@gmail.com; https://orcid.org/0000-0001-5327-9824
Similar Articles
