Coronavirus infection and viruses of the Herpesviridae family


DOI: https://dx.doi.org/10.18565/epidem.2022.12.2.65-9

Asfandiyarova N.S.

Academician I.P. Pavlov Ryazan State Medical University, Ministry of Health of Russia, Ryazan, Russia
The Herpesviridae family of viruses includes 9 serotypes that cause a variety of clinical manifestations, but share the common property: their infection or reactivation is observed in immunocompromised individuals. Due to the presence of angiotensin-converting enzyme receptors in the immunocompetent cells, through which the virus enters the cells, coronavirus infection causes their damage, contributing to immune system dysregulation. The consequence of this is Herpesviridae infection or reactivation. Various markers of herpesvirus infection are found in 20-70% of patients with coronavirus infection. An analysis of literature data may suggest that human herpes viruses are immune system dysregulation markers that certainly diminish quality of life, but worsen the course of the pathological process in patients with coronavirus infection, perhaps, only herpes simplex virus type 1, cytomegalovirus, and Kaposi sarcoma-associated virus.

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About the Autors


Nailia S. Asfandiyarova, MD, Associate Professor, Department of Outpatient Therapy, Preventive Medicine, and General Medical Practice, Ryazan State Medical University, Ryazan, Russia; n.asfandiyarova2010@yandex.ru; http://orcid.org/0000-0002-2025-8119; eLibrary SPIN: 1095-4892


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