Herd immunity to measles, rubella, and mumps viruses in the population of Moscow in 2016–2017


DOI: https://dx.doi.org/10.18565/epidem.2019.9.2.31-8

Nozdracheva A.V., Semenenko T.A., Rusakova E.V., Guseva E.V., Ivanova M.Yu., Gotvyanskaya T.P.

1) Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia, Moscow, Russia; 2) I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia
With obvious successes in the control of measles, rubella and mumps, today it has become extremely relevant to establish what aggravates the epidemic situation of these infections in Russia and European countries.
Objective. To estimate the immunological structure of the Moscow population to vaccine-preventable infections.
Materials and methods. Epidemiological, statistical, and serological (including 1951 serum samples) methods were used.
Results. In 2016–2017, among the total Moscow population, the immune stratum to measles, rubella, and mumps viruses averaged 54.2% [95% CI, 51.9–56.4], 89.1% [95% CI 87.7–90.5], and 69.5% [95% CI, 67.5–71.6], respectively. The proportion of persons immune to the causative agents of the above infections varied according to age; children and young people (their mean age was less than 35 years) are more susceptible than those in older age groups.
Conclusion. When non-immune children and young people get older, there may be an increase in the proportion of people susceptible to measles, rubella, and mumps among the Moscow adult population, which necessitates additional vaccination among the population previously unvaccinated.

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About the Autors


Anna V. Nozdracheva, Researcher, Department of Epidemiology, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; е-mail: nozdracheva0506@gmail.com; ORCID: http://orcid.org/ 0000-0002-8521-1741
Prof. Tatiana A. Semenenko, MD, Academician of the Russian Academy of Natural Sciences, Head, Department of Epidemio­logy, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; Professor, Department of Infectology and Virology, Faculty of Preventive Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia; e-mail: semenenko@gamaleya.org; ORCID: http://orcid.org/0000-0002-6686-9011
Prof. Ekaterina V. Rusakova, MD, Leading Researcher, Scientific and Organizational Department, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; e-mail: Rusakovaev5@yandex.ru; ORCID: http://orcid.org/0000-0002-3561-1499
Elena V. Guseva, Cand. Biol. Sci., Leading Researcher, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; e-mail: guseva@gamaeya.org; ORCID: http://orcid.org/0000-0003-0931-9854
Marina Yu. Ivanova,  Cand. Med. Sci., Associate Professor, Department of Histology, Cytology and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia; e-mail: ivanova_m_y@mail.ru; ORCID: http://orcid.org/ 0000-0002-7696-9809
Tatiana P. Gotvyanskaya, Cand. Biol. Sci., Senior Researcher, Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia, Moscow, Russia; Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; e-mail: gotvin@gamaleya.org; ORCID: http://orcid.org/0000-0002-0814-2666


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