Cagocel® treatment of influenza and other respiratory viral infections


Eganyan G.A., Arutyunyan S.K., Grigoryan S.S., Khizanyan N.S., Sukiasyan S.M., Gevorgyan Zh.K., Maksudyan N.A., Gasparyan A.Z., Donbayan D.A., Ambartsumyan K.G., Papoyan Zh.R., Karakhanyan A.S., Karapenyan M.G., Kazaryan E.R.

M.Geratsi Yerevan State Medical University; Surb Grigor Lusavorich Medical Center, Yerevan; Erebuni Medical Center, Yerevan; Armenia Medical Center, Yerevan; Polyclinic Seventeen, Yerevan; Polyclinic One, Yerevan; Zvartnots Polyclinic, Yerevan
Objective. To study the clinical efficiency and possible side effects of the use of cagocel®, a drug from the group of interferon inductors, to treat influenza and other respiratory virus infections.
Subjects and methods. A multicenter observational study was conducted in 120 patients aged 3 to 62 years with clinical signs of acute respiratory diseases, such as rhinopharyngitis, rhinopharyngitis with tracheobronchitis or rhinopharyngitis with tracheobronchitis with signs of bronchial obstruction. The patients were divided into 2 groups: 1) a study group and 2) a comparison group; each group comprised 60 patients. Besides traditional symptomatic treatment, Group 1 took cagocel® in the doses given in the instruction. Group 2 received symptomatic treatment only.
Results. The study established a significantly noticeable reduction in fever and catarrhal signs in the nasopharynx and trachea in Group1 versus Group 2. Complications as tracheobronchitis and bronchopneumonia were significantly less common in Group 1. Adverse reactions (abdominalgia, dyspepsia, diarrhea, constipation, etc.), changes in the count of red blood cells, white blood cells, or platelets in peripheral blood, and increases in the activity of hepatic enzymes and in the content of total bilirubin in plasma were seen in none of the patients in Group 1.
Conclusion. Cagocel® is effective and safe in treating influenza and other acute respiratory virus infections.

About the Autors


Prof. Yeganyan Gagik Azatovich, MD; Department of Therapy, M. Geratsi Yerevan State Medical University; Principal Therapist, Ministry of Health of the Republic of Armenia
Address: 2, Koryun St., Erevan 0025, Republic of Armenia
Telephone: (37410) 47-24-70
E-mail: gayeganyan@mail.ru


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