Clinical and laboratory features of abnormalities in the cervix uteri, external genitals, and vagina in HIV-infected patients
Sundukov A.V., Gafurov Yu.T., Evsyukov O. A.
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; Infectious Diseases Clinical Hospital Two, Moscow Healthcare Department
Objective. To reveal the clinical and laboratory features of abnormalities in the cervix uteri, external genitals, and vagina in HIV-infected patients.
Subjects and methods. The study enrolled 411 HIV-infected patients who had sought gynecologic care at Infectious Diseases Clinical Hospital Two, Moscow Healthcare Department, in 2006 to 2011. Groups 1 and 2 included 259 and 152 patients who had sought gynecologic care for abnormalities in external genitals and vagina, respectively.
Results. In Group 1, the HIV-infected patients were more frequently found to have cervical dysplasia and cancer. In Group 2, the reason for seeking the care was external genital and vaginal warts in 49.3% of the patients. Antiretroviral therapy (ARVT) along with surgical removal of warts could achieve a two-year relapse-free period in 94.7% of the patients.
Conclusion. Cervical dysplasia and cancer are more frequently registered in the HIV-infected patients than in the general population. The detection rate of external genital and vaginal warts depends on the stage of HIV infection. ARVT and surgical removal of warts contributes to the increased duration of a relapse-free period.
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About the Autors
Prof. Sundukov Aleksandr Vadimovich, MD; Department of Communicable Diseases and Epidemiology, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Address: 15, Eighth Sokolinaya Gora St., Moscow 105275
Telephone: +7(495) 365–24–85