Русский
Clonal groups of uropathogenic Escherichia coli isolated in the Russian Federation in 2004–2019.
DOI: https://dx.doi.org/10.18565/epidem.2024.14.1.55-61
Slukin P.V., Fursova N.K., Svetoch E.A., Perepanova T.S., Ershova M.G., Poletaeva E.D., Kruglov A.N., Priputnevich T.V.
1) State Scientific Center for Applied Microbiology and Biotechnology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Obolensk, Moscow Region, Russia; 2) N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Radiological Center, Ministry of Health of Russia, Moscow, Russia; 3) Infectious Clinical Hospital № 1, Yaroslavl, Russia; 4) Moscow Multidisciplinary Clinical Center «Kommunarka» of the Moscow Healthcare Department, Moscow, Russia; 5) Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia
Materials and methods. E. coli strains (n = 303) isolated in 2004–2019 from urine samples of patients with urological diagnoses. The microbiological, molecular genetic and bioinformatic methods for assessing resistance and virulence, as well as molecular genetic methods for identifying phylogenetic groups, O-groups and sequence types were used in the study.
Results. The widespread distribution of uropathogenic strains of the O25-B2-ST131 clonal group in Russia has been shown; in addition, O2-B2-ST141, O89-A-ST744, O4/O6-B2-ST127, B1-ST58, D-ST69, O2/O6-B2-ST73, A-CC10 and O75-B2-CC14clonal groups have been identified.
Conclusion. Assessing the distribution of clonal groups of uropathogenic strains in Russia allows to assess the epidemic situation, predict its development in the future, and also determine the optimal directions of therapy.
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About the Autors
Pavel V. Slukin, Researcher, Department of Molecular Microbiology, State Scientific Center for Applied Microbiology and Biotechnology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Obolensk, Russia; xopgi@yandex.ru; http://orcid.org/0000-0002-4976-0145
Nadezhda K. Fursova, Cand. Biol. Sci., Leading Researcher, Department of Molecular Microbiology, State Scientific Center for Applied Microbiology and Biotechnology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Obolensk, Russia; n-fursova@yandex.ru; http://orcid.org/0000-0001-6053-2621
Professor Eduard A. Svetoch, DVSc, Chief Researcher, Department of Molecular Microbiology, State Scientific Center for Applied Microbiology and Biotechnology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Obolensk, Russia; svetoch@obolensk.org; http://orcid.org/0000-0002-3185-1954
Professor Tamara S. Perepanova, МD, Head, Group of Infectious and Inflammatory Diseases and Clinical Pharmacology, N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Radiological Center, Ministry of Health of Russia Moscow, Russia; perepanova2003@mail.ru; http://orcid.org/000-0002-2877-0029
Marina G. Ershova, Head, Microbiological Laboratory, 3Infectious Clinical Hospital № 1, Yaroslavl, Russia; mary.erschowa2013@yandex.ru; http://orcid.org/0000-0003-4691-648X
Elena D. Poletaeva, Bacteriologist, Infectious Clinical Hospital No. 1, Yaroslavl, Russia; mary.erschowa2013@yandex.ru; http://orcid.org/0000-0002-7074-6989
Aleksandr N. Kruglov, Cand. Biol. Sci., Senior Researcher, Head, Laboratory of Clinical Microbiology, Moscow Multidisciplinary Clinical Center «Kommunarka», Moscow Healthcare Department, Moscow, Russia; kruglov_a_n@mail.ru; http://orcid.org/0000-0001-6849-0008
Professor Tatyana V. Priputnevich V., Corresponding Member of the Russian Academy of Sciences, МD, Director, Institute of Microbiology of Antimicrobial Therapy and Epidemiology, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia; t_priputnevich@oparina4.ru; http://orcid.org/0000-0002-4126-9730
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