Русский
Risk factors for nonadherence to follow-up monitoring and treatment of HIV infection: results of a survey of patients who start treatment and those who have undergone antiretroviral therapy
DOI: https://dx.doi.org/10.18565/epidem.2020.10.3.94-8
Bеlyaeva V.V., Kozyrina N.V., Pokrovskaya A.V.
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
Subjects and methods. A total of 311 HIV-infected patients (209 men and 102 women) were interviewed. Group 1 consisted of 241 patients who had undergone treatment; Group 2 included 70 patients who started HIV treatment for the first time. Quality of life was assessed according to the Short Form-36 (SF-36) Questionnaire and the General Health Self-Assessment Questionnaire. Depressive disorder and HIV therapy satisfaction were determined using the Center for Epidemiologic Studies Depression Scale (CES-D) and the HIV Treatment Satisfaction Questionnaire (HIVTSQ).
Results. There were no statistically significant differences in the data obtained in the groups according to the scales of physical functioning and role functioning related to the physical status. The scores of the scale of role functioning related to the emotional status were significantly lower in Group 2 (76.54 ± 35.23 versus 87.07 ± 26.8 in Group 1). There was no statistically significant difference in the number of patients having high depression scale scores; however, such patients were more in Group 2. Complete therapy satisfaction was reported by 25.7% of the respondents in Group 1.
Conclusion. The investigation has shown emotional vulnerability in the patients starting treatment for the first time, as well as antiretroviral therapy dissatisfaction in those who have undergone HIV treatment. The techniques that can assess the presence of a depressive disorder, quality of life in patients, and their therapy satisfaction will help to clarify the scope and contents of measures aimed at preventing the risks for impairment and replenishment of the resources for maintaining adherence to follow-up monitoring and disease treatment.
Literature
1. Ладная Н.Н., Покровский В.В., Дементьева Л.А, Соколова Е.В., Козырина Н.В., Нарсия Р.С. ВИЧ-инфекция в Российской Федерации в 2018 г. Материалы международной научно-практической конференции «Актуальные вопросы ВИЧ-инфекции». Санкт-Петербург, 2019; 3–12. Ladnaia N.N., Pokrovskiy V.V., Dementieva L.A, Sokolova E.V., Kozyrina N.V., Narsia R.S. [HIV infection in the Russian Federation in 2018]. Materials of the international scientific and practical conference «Current issues of HIV infection». Saint-Petersburg, 2019; 3–12. (In Russ.) 2. Беляков Н.А., Рассохин В.В., Колбин А.С., Ди Клементе Р.Д., Пантелеев А.М., Азовцева О.В., Огурцова С.В., Симакина О.Е., Степанова Е.В., Вяльцин С.В., Жолобов В.Е., Ковеленов А.Ю., Мельникова Т.Н., Курганова Т.Ю., Улумбекова Г.Э. Эпидемиологическая, клиническая и финансовая составляющие результатов многолетней антиретровирусной терапии пациентов с ВИЧ-инфекцией. ВИЧ-инфекция и иммуносупрессии 2019; 11(4): 7–19. https://doi.org/10.22328/2077-9828-2019-11-4-7-19 Belyakov N.A., Rassohin V.V., Kolbin A.S., DiKlemente R.D., Panteleev A.M., Azovceva O.V., Ogurcova S.V., Simakina O.E., Stepanova E.V., Vialcin S.V., Zholobov V.E., Kovelenov A.Y., Melnikova T.N., Kurganova T.Y., Ulumbekova G.E. [Epidemiological, clinical and financial components of the results of long-term antiretroviral therapy of patients with HIV infection]. VICh-infektsiya i immunosupressii 2019; 11(4): 7–19. (In Russ.). https://doi.org/10.22328/2077-9828-2019-11-4-7-19 3. Кольцова О.В., Сафонова П.В., Рыбников В.Ю., Штерн М.А. Личностные особенности и поддержание непрерывности лечения у ВИЧ-инфицированных пациентов. Вестник Санкт-Петербургского университета. Сер. 16. 2013; вып. 4: 49–59. Kolcova O.V., Safonova P.V., Rybnikov V.Y., Shtern M.A. [Personal characteristics and maintenance of treatment continuity in HIV-infected patients]. Vestnik Saint Petersburgskogo Universiteta. Ser. 16. 2013; Issue 4: 49–59. (In Russ.) 4. Сирота Н.А., Ющук Н.Д., Федяева О.Н. Проблема низкой приверженности АРВТ у больных ВИЧ-инфекцией и способы их выявления. Клиническая и медицинская психология: исследования, обучение, практика: электрон. науч. журн. 2014; 3(5): 10. http://www. medpsy.ru/climp/2014_3_5/article11.php Sirota N.A., Yushhuk N.D., Fediaeva O.N. [The problem of low adherence to anti-virus treatment among patients with HIV infection and ways to detect them]. Klinicheskaya i meditsinskaya psikhologiya: issledovaniya, obucheniye, praktika: online scientific journal. 2014; 3(5): 10. (In Russ.). http://www. medpsy.ru/climp/2014_3_5/article11.php 5. Соколова Е.В., Беляева В.В. Особенности использования термина «приверженность» в современной отечественной научно-практической литературе, посвященной инфекционным заболеваниям. Журн. инфектол. 2019; 11(3, приложение 1): 94–7. Sokolova E.V., Belyaeva V.V. [Features of the use of the term «commitment» in modern Russian scientific and practical literature on infectious diseases]. Zhurnal infektologii 2019, 11(3, Suppl. 1): 94–7. (In Russ.). 6. Новохацки А.В. Особенности переживания применения антиретровирусной терапии у ВИЧ-инфицированных. Вестник ЮУрГУ 2009; 42(7): 62–7. Novohacki A.V. [Features of the experience of using antiretroviral therapy in HIV-infected people]. Vestnik Yuzhno-Uralskogo gosudarstvennogo universiteta 2009; 42(7): 62–7. (In Russ.). 7. Дессау М.И., Лиознов Д.А., Николаенко С.Л., Беляева Т.В. Стигматизация, качество жизни, приверженность диспансерному наблюдению и лечению больных ВИЧ-инфекцией. Инфекционные болезни: новости, мнения, обучение 2017; (4): 76–81. Dessau M.I., Lioznov D.A., Nikolaenko S.L., Belyaeva T.V. [Stigmatization, quality of life, and commitment to follow-up and treatment of HIV patients]. Infektsionnyye bolezni: novosti, mneniya, obucheniye 2017; (4): 76–81. (In Russ.). 8. Москвичева М.Г., Радзиховская М.В. Сравнительная оценка качества жизни ВИЧ-инфицированных пациентов, получающих первичную специализированную медицинскую помощь на амбулаторном и стационарном этапах (по данным социологического опроса). Инфекционные болезни: новости, мнения, обучение 2015; (3): 104–9. Moskvicheva M.G., Radzihovskaya M.V. [Comparative assessment of the quality of life of HIV-infected patients receiving primary specialized medical care at the outpatient and inpatient stages (according to a sociological survey)]. Infektsionnyye bolezni: novosti, mneniya, obucheniye 2015; (3): 104–9. (In Russ.).
About the Autors
Valentina V. Belyaeva МD, Leading Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: labora-et-ora@yandex.ru; ORCID: http://orcid.org/ 0000-0002-4621-7892
Nadezhda V. Kozyrina, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: nad-kozyrina@yandex.ru; ORCID: http://orcid.org/0000-0001-5134-0054
Anastasia V. Pokrovskaya, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; e-mail: pokrovskaya_av@mail.ru; ORCID: http://orcid.org/0000-0002-2677-0404
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