Vaccines for the prevention of pneumococcal infections: a case study of adults from organized collectives


DOI: https://dx.doi.org/10.18565/epidem.2018.4.72-81

Zaitsev A.A., Akimkin V.G., Briko N.I.

1 Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defense of the Russian Federation, Moscow, Russia; 2 Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 3 I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia
Pneumococcal infections are an important problem for organized collectives. The incidence of pneumonia among the servicemen of different military and security forces remains high (30–50‰), whereas the pneumococcus is the most common microbiological finding in young patients with pneumonia from the organized groups. Severe invasive pneumococcal infections, the treatment of which requires significant resources from practical health care, are also a serious problem. Many countries of the world adopt a restrained attitude towards the prevention of pneumococcal diseases by vaccination in the servicemen; however, necessary vaccination against severe invasive pneumococcal infections in the security forces of Russia is a very important event according to the authors of this publication. The use of pneumococcal vaccines in the servicemen results in a decline in the number of severe pneumococcal pneumonia cases.
Keywords: adults from organized collectives, pneumococcal infections, armed forces personnel, pneumonia
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Literature

  1. Baranov A.Ф., Namazova-Baranova L.S., Brico N.I., Chuchalin A.G., Tatochenko V.K., Kharit S.R., Fedoseyenko M.V., Polibin R.V., Sukhova V.A., Vishneva E.A., Selimzyanova L.R. [Vaccine prophylaxis of pneumococcal infection. Federal Clinical Recommendations]. Moscow, 2015. URL: http://nasci.ru/_resources/directory/201/common/2015_4_ Pnevmo _vak_new.pdf (In Russ.).
  2. Porat N., Trefler R., Dagan R. Persistence of two invasive Streptococcus pneumoniae clones of serotypes 1 and 5 in comparison to that of multiple clones of serotypes 6B and 23F among children in southern Israel. J. Clin. Microbiol. 2001; 39(5): 1827–32. DOI:10.1128/jcm.39.5.1827-1832.2001
  3. Bewick T., Sheppard C., Greenwood S., Lack M., Trotter C., George R., Lim W.S. Serotype prevalence in adults hospitalised with pneumococcal non-invasive community-acquired pneumonia. Thorax 2012; 67(6): 540–5. DOI: 10.1136/thoraxjnl-2011-201092
  4. Lobzin Y., Sidorenko S., Harit S., Belanov S.S., Volkova M.O., Gostev V.V.,Alekseyenko S.I., Petrova S.I., Sergeyeva E.V., Koroleva I.S., Orlov A.V., Frolova E.Ya. [Serotypes of Streptococcus pneumoniae, which cause leading clinical forms of pneumococcal infections]. Zhurnal infektologii 2013; 5(4): 35–41. (In Russ.).
  5. Chuchalin A.G., Bilichenko T.N., Osipova G.L., Kurbatova E.A., Egorova N.B., Kostinov M.P. [Vaccine prophylaxis of respiratory diseases in the framework of primary health care to the population]. Pulmonologiya 2015; 25(2): 1–19. (In Russ.).
  6. Beloshitsky G.V., Koroleva I.S., Koshkina N.A. [Pneumococcal meningitis in the Russian Federation]. Epidemiologiya i vaktsinoprofilaktika 2009; (2): 21–6. (In Russ.).
  7. Mandell L., Wunderink R., Anzueto A., Bartlett J.G., Campbell G.D., Dean N.C. et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clin. Infect. Dis. 2007; 44 (Suppl 2): S27–72.
  8. [Clinical guidelines for the diagnosis, treatment and prevention of severe community-acquired pneumonia in adults]. Moscow, 2014 URL: https://mzdrav.rk.gov.ru/file/Klinicheskie_rekomendacii.pdf (In Russ.).
  9. Ovchinnikov Yu.V., Zaitsev A.A., Sinopalnikov A.I.. Kryukov E.V., Kharitonov M.Yu., Chernov S.A., Makarevich A.M. [Community-acquired pneumonia among military personnel: tactics of reference and antimicrobial therapy]. Voyenno-meditsinskiy zhurnal 2016; (3): 4–14. (In Russ.).
  10. Maruyama T., Fujisawa T., Suga S., Nakamura H., Nagao M., Taniguchi K., et al. Outcomes and Prognostic Features of Patients With Influenza Requiring Hospitalization and Receiving Early Antiviral Therapy: A Prospective Multicenter Cohort Study. Chest 2016; 149: 526–34. DOI: 10.1378/chest.14-2768
  11. Zaitsev A.A., Schegolev А.V., [Severe lung lesions with influenza A (H1N1). Practical recommendations]. Voyenno-meditsinskiy zhurnal 2016; (3): 39–46. (In Russ.).
  12. Bilichenko T.N., Argunova A.N., Antonova O.A., Solovyev K.I., Gladin S.A., Nikitina N.N., Lyamin A.V., Chigishchev A.P., Puchkina N.E. [The incidence of pneumococcal pneumonia in adult patients in therapeutic hospitals in the three territories of the Russian Federation]. Pulmonologiya 2013; (4): 30–6. (In Russ.).
  13. Sinopalnikov A.I., Zaitsev A.A. [Analysis of the state of pulmonological aid in the Armed Forces and ways to improve it]. Voyenno-meditsinskiy zhurnal 2008; (8): 31–40. (In Russ.).
  14. Shubin I.V. [The urgency of vaccine prophylaxis for pneumococcal infection in organized collectives of servicemen]. Vestnik sovremennoy klinicheskoy meditsiny 2017; 10: 36–42. (In Russ.).
  15. Biedenbach D., Badal R., Huang M., Motyl М., Singhal P.K., Kozlov R.S. et al. In Vitro Activity of Oral Antimicrobial Agents against Pathogens Associated with Community-Acquired Upper Respiratory Tract and Urinary Tract Infections: A Five Country Surveillance Study. Infect. Dis. Ther. 2016; 5(3): 405. DOI: 10.1007/s40121-016-0112-3
  16. Crum N., Wallace M., Lamb C., Conlin A.M., Amundson D.E., Olson P.E. et al. Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. Am. J. Prev. Med. 2003; 25: 107–11.
  17. Belevitin A.B., Akimkin V.G., Mosyagin V.D. [Organizational-epidemiological aspects of prevention of community-acquired pneumonia in military collectives]. Voyenno-meditsinskiy zhurnal 2009; (9): 56–63. (In Russ.).
  18. Guchev I.A., Klochkov O.I., Sinopalnikov A.I. [Prevention of outbreaks of community-acquired pneumonia with polysaccharide pneumococcal vaccine: analysis of perspectives of use for power structures of Russia]. Antibiotiki i khimioterapiya 2016; 61(1–2): 43–52. (In Russ.).
  19. Vainio A., Lyytika е O., Skyttä R., Kaijalainen T., Teirilä L., Rantala M. et al. An outbreak of pneumonia associated with S. pneumoniae at a military training facility in Finland in 2006. APMIS 2009; 117(7): 488–91. DOI: 10.1111/j.1600-0463.2009.02463.x.
  20. Zhogolev S.D., Ogarkov P.I., Efimov E.I. [Development of the epidemic process of community-acquired pneumonia among military personnel]. Vestnik Rossiyskoy voyenno-meditsinskoy akademii 2008; 2(22): 269–70. (In Russ.).
  21. Korzeniewskia K., Nitsch-Osuchb A. Respiratory tract infections in the military environment. Respiratory Physiology & Neurobiology. 2015; 209: 76–80. DOI: 10.1016/j.resp.2014.09.016
  22. Ovchinnikov Yu.V., Zaitsev A.A., Sinopalnikov A.I., Shchegolev A.V., Kryukov E.V., Zhdanov K.V., Khrapov K.N., Chernov S.A., Makarevich A.M. [Diagnosis, treatment and vaccine prophylaxis of community-acquired pneumonia among military personnel. Methodical instructions for the treatment of community-acquired pneumonia among military personnel]. Moscow: Glavnyy voyenno-klinicheskiy gospital imeni N.N. Burdenko, 2015. (In Russ.).
  23. Levine H., Balicer R.D., Zarka S., Sela T., Rozhavski V., Cohen D. et al. Dynamics of pneumococcal acquisition and carriage in young adults during training in confined settings in Israel. PLoS One 2012; 7(10): e46491. DOI: 10.1371/journal.pone.0046491
  24. Balicer R., Zarka S., Levine H., Klement E., Sela T., Porat N. et al. Control of Streptococcus pneumoniae serotype 5 epidemic of severe pneumonia among young army recruits by mass antibiotic treatment and vaccination. Vaccine 2010; 28(34): 5591–6. DOI: 10.1016/j.vaccine.2010.06.031.
  25. Falkenhorst G., Remschmidt C., Harder T., Hummers-Pradier E., Wichmann O., Bogdan C. et al. Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis. PLoS One 2017; 12(1): e0169368. DOI: 10.1371/journal.pone.0169368
  26. Hak E., Grobbee D.E., Sanders E., Verheij T.J.M., Bolkenbaas M., Huijts S.M. et al. Rationale and design of CAPITA: a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults. Neth. J. Med. 2008; 66(9): 378–83.
  27. Huijts S., van Werkhoven C., Bolkenbaas M., Grobbee D.E., Bonten M.J.M. Post-hoc analysis of a randomized controlled trial: Diabetes mellitus modifies the efficacy of the 13-valent pneumococcal conjugate vaccine in elderly. Vaccine 2017; 34: 4444–49. DOI: 10.1016/j.vaccine.2017.01.071
  28. McLaughlin J., Jiang Q., Isturiz R., Sings H.L., Swerdlow D.L., Gessner B.D. et al. Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine Against Hospitalization for Community-Acquired Pneumonia in Older US Adults: A Test-Negative Design. Clin. Infect. Dis. 2018; May 21. DOI: 10.1093/cid/ciy312.
  29. Rossi K., Nowak G., Riegodedios A. Pneumonia at Marine Corps Recruit Depots: Current Trends in Ambulatory Encounters and Inpatient Discharges. Mil. Med. 2017; 182(3): e1733–40. DOI: 10.7205/MILMED-D-16-00034.
  30. Russell K.L., Baker C.I., Hansen C., Poland G.A., Ryan M.A.K. et al. Lack of effectiveness of the 23-valent polysaccharide pneumococcal vaccine in reducing all-cause pneumonias among healthy young military recruits: A randomized, double-blind, placebo-controlled trial. Vaccine 2015; 33(9): 1182–7. DOI: 10.1016/j.vaccine.2014.12.058
  31. Muraviev A.A., Kozlov R.S., Lebedeva N.N. [Epidemiology of S. pneumoniae serotypes in the territory of the Russian Federation]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya 2017; 19(3): 200–6. (In Russ.).
  32. Lobzin Yu.V., Sidorenko S.V., Harit S.M., Belanov S.S., Volkova M.O., Gostev V.V., Alekseyenko S.I., Petrova S.I., Sergeyeva E.I., Koroleva I.S., Orlov A.V., Frolova E.Ya. [Serotypes of Streptococcus pneumoniae, which cause leading forms of pneumococcal infections]. Zhurnal infektologii 2013; 5(4): 36–42. DOI: 10.22625/2072-6732-2013-5-4-36-42 (In Russ.).
  33. Beloshitsky G.V., Koroleva I.S. [Serotype characterization of S. pneumoniae strains in Moscow]. Epidemiologiya i vaktsinoprofilaktika 2014; 74(1): 90–7. (In Russ.).
  34. Martynova A.B., Balabanova L.A., Chulakova O.A. [Multilocus typing of Streptococcus pneumoniae strains isolated from elderly patients with community-acquired pneumonia]. Byulleten sibirskoy meditsiny 2014; 13(3): 40–5. (In Russ.).
  35. Feldblum I.V., Semerikov V.V., Golodnova S.O., Nikolenko V.V., Zagarova Yu.A., Vorobyeva N.N. Serotyping of Str. pneumoniae, circulating in the territory of Perm. Zdorovye semi – 21 vek 2013; 2(15): 194–203. URL: http://www.fh-21.perm.ru/download/ 2013-2-15.pdf (In Russ.).
  36. Sabanin Yu.V., Rikhter V.V., Rybin V.V., Baryshev S.N., Kuzin S.N. [Vaccine prophylaxis of community-acquired pneumonia in internal troops of the Ministry of Internal Affairs of Russia]. Voyenno-meditsinskiy zhurnal 2008; 9(4): 70–1. (In Russ.).
  37. Shubin I.V. [Experience in the use of vaccine prophylaxis pneumococcal infection in organized collectives of military personnel]. Vestnik sovremennoy klinicheskoy meditsiny 2016; 9(6): 103–8. (In Russ.).
  38. Kozlov R.S.. Avdeyev S.N.. Briko N.I.. Bilichenko T.N.. Kostinov M.P.. Sidorenko S.V.. Kharit S.M.. Sinopalnikov A.I.. Zaytsev A.A.. Shubin I.V.. Demko I.V.. Ignatova G.L.. Rachina S.A.. Feldblum I.V. [Vaccination of pneumococcal infections in adults. Resolution of the Council of experts (Moscow, 16 December 2017)]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya 2018; 20(1): 5–8.

For citations: Zaytsev A.A., Akimkin V.G., Briko N.I. Vaccines for the prevention of pneumococcal infections: a case study of adults from organized collectives. Èpidemiologiâ i infekcionnye bolezni. Аktual’nye voprosy 2018; (4):72–81 (In Russ.).


About the Autors

Prof. Andrey A. Zaytsev, MD, Principal Pulmonologist, Academician N.N. Burdenko Main Military Clinical Hospital; Principal Pulmonologist, Ministry of Defense of the Russia, Моscow, Russia; е-mail: a-zaicev@yandex.ru; ОRCID: http://orcid.org/0000-0002-0934-7313
Prof. Vasiliy G. Akimkin, MD, Аcademician of the Russian Academy of Sciences, Director, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; e-mail: vgakimkin@yandex.ru; ОRCID: http://orcid.org/0000-0003-4228-9044
Prof. Nikolay I. Briko, MD, Аcademician of the Russian Academy of Sciences; Honored Scientist of the Russian Federation; Head, Department of Epidemiology and Evidence-Based Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia; е-mail: nbrico@mail.ru; ORCID ID: 0000-0002-6446-2744


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