A follow-up of patients with HCV-infection markers in the rural infectious diseases room of a rural area
DOI: https://dx.doi.org/10.18565/epidem.2018.2.75-81
Ginyatullin R.R., Kitaev M.R., Vafin A.Yu., Kravchenko I.E.
1 Kazan State Medical University, Ministry of Health of Russia, Kazan, Russia;
2 Rybno-Slobodsky Central District Hospital, Ministry of Health of the Republic of Tatarstan, Russia
Objective. To develop ways to improve the efficiency of patient follow-up in the infectious diseases room of a rural area, by analyzing the results of prophylactic medical examination of patients with HCV-infection markers.
Materials and methods. The authors investigated the results of clinical and laboratory instrumental studies in patients with HCV-infection markers, who had been registered in the infectious diseases room of a rural area, as well as the incidence rates of chronic hepatitis C (CHC) in the municipal district of the Republic of Tatarstan according to the 2005–2016 official statistics.
Results. The investigation revealed a low follow-up coverage and a low availability of up-to-date laboratory diagnostic techniques. The introduction of PCR in the examination algorithm led to an improvement in the diagnosis of CHC, which increased its morbidity rates in the municipal district. The distribution of patients with CHC in dispensary groups was justified to optimize the follow-up.
Conclusion. The introduction of a PCR detection test in the algorithm of examination of patients with markers of HCV infection and their distribution in dispensary groups increases the level of diagnosis of CHC and the efficiency of a follow-up.
Literature
- Global Report on Access to Hepatitis C Treatment: Focus on overcoming barriers WHO reference number: WHO/HIV/2016.20. http://www.who.int/hepatitis/publications/hep-c-access-report/en
- Mukomolov S.L., Levakova I.A., Sulyagina L.G., Sinaiskaya E.V., Bolsun D.D., Ivanova N.V. Modern epidemiology of hepatitis C in Russia. Èpidemiologiâ i infekcionnye bolezni. Аktual’nye voprosy 2012; (6): 21–5. (In Russ.).
- Pimenov N.N., Vdovin A.V., Komarova S.V., Mamonova N.A., Chulanov V.P., Pokrovsky V.I. [Applicability and prospects of united federal register of patients with viral hepatitis B and C introduction in Russia]. Terapevticheskiy arkhiv 2013; (11): 4–9. (In Russ.).
- Volchkova E.V. Medical social aspects of viral hepatitis with parenteral transmission. Epidemiologiya i infectionnye bolezni 2013; (1): 38–9. (In Russ.).
- [Epidemiological atlas PFD. Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being.] http://epid-atlas.nniiem.ru/a01_data_main.html#. (In Russ.).
- Serenko K.A. [Medical, social, clinical and economic aspects of chronic hepatitis C.]. Cand. Med. Dis. Moscow, 2011. http://www.dissercat.com/content/mediko-sotsialnye-i-kliniko-ekonomicheskie-aspekty-khronicheskogo-gepatita-s (In Russ.).
- Sewell J.L., Guy J., KwonA., Chen A.H., Yee H.F., Jr. Preconsultation exchange for ambulatory hepatology consultations. Am. J. Med. 2013; 126(6): 523–8.
- Chulanov V.P., Pimenov N.N., Komarova S.V. [Hepatitis C in Russia: epidemiological characteristics and ways to improve diagnostics and control]. Epidemiologiya i infekcionnye bolezni 2012; (3): 4–9. (In Russ.).
- Cloherty G., Talal A., Coller K., Steinhart, C., Hackett, J., Jr., Dawson G. et al. Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection. J. Clin. Microbiol. 2016; 54(2): 265–73.
- Enaleeva D.Sh., Fazylov V.K., Sozinov A.S. [Chronic viral hepatitis B, C and D. A guide for doctors]. Moscow: GEOTAR-Media, 2015. 192 p. (In Russ.).
- Ivashkin V.T., Ushchuk N.D., Klimova E.A., Maevskaya M.V., Chulanov V.P. et al. [Recommendations for the diagnosis and treatment of adult patients with hepatitis C]. Moscow, 2014. https://arvt.ru/sites/ default/files/rf-recom-gep-C-2014.pdf (In Russ.).
- [Chronic viral hepatitis C (CVHC) in adults. Clinical guidelines. International Association of Specialists Regarding Infection (IASRI)] Moscow, 2016. http://iia-rf.ru/upload/pdf/КР380_Гепатит%20С_ ИЮ%20допол.pdf (In Russ.).
- Enaleeva D.Sh., Fazylov V.Kh. [The role of primary care physicians in the diagnosis and medical examination of patients with chronic viral hepatitis B, C and D]. Kazanskiy meditsinskiy zhurnal 2014; 95(3): 439–45. (In Russ.).
- Yastrebova O.N. [Hepatitis C. Informational and methodical manual.]. Novosibirsk: Vector-Best, 2003. 44 p. (In Russ.).
- Semendyaeva M.I., Merkulov I.A., Pastukhov A.I., Gaidasheva E.V., Lesnyak V.N., Shutova O.V. [Hepatocellular carcinoma – day today]. Klinicheskaya praktika 2013; (2): 35–49. (In Russ.).
- Bugaeva T.T., Alekseeva M.N., Ivanov P.M., Sleptsova S.S., Karataev P.D. [Chronic viral hepatitis as the main risk factors for hepatocellular carcinoma in Yakutia]. Sibirskiy Meditsinskiy Zhurnal 2007; (2): 47–8. In Russ.).
- Ghany M., Nelson D., Strader D., Thomas D., Seeff L. An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guideline by the American Association for the Study of Liver Diseases. Hepatology 2011; 54(4):, 1433–44.
- Boursier J., de Ledinghen V., Zarski J.P., Fouchard-Hubert I., Gallois Y., Oberti F. et al. Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive. Hepatology 2012; 55(1): 58–67.
- Marsellin P. Hepatitis C: The clinical spectrum of the disease. J. Hepatol. 1999; 31(Suppl. 1): 9–16.
For citations: Ginyatullin R.R., Kitaev M.R., Vafin A.Yu., Kravchenko I.E. A follow-up of patients with HCVinfection markers in the rural infectious diseases room of a rural area. Èpidemiologiâ i infekcionnye bolezni. Аktual’nye voprosy 2018; (2):75–81
About the Autors
For correspondence:
Rinat R. Gineatullin, Postgraduate Student, Department of Infectious Diseases, Kazan State Medical University, Ministry of Health of Russia; Infectiologist, Rybno-Slobodsky Central District Hospital, Ministry of Health of the Republic of Tatarstan
Address: 49, Butlerova St., Kazan 420012, Republic of Tatarstan, Russia
Е-mail: big2garin@gmail.com
Information about the authors:
Mansur R. Kitaev, Cand. Med. Sci., Chief Physician, Rybno-Slobodsky Central District Hospital, Ministry of Health of Republic of Tatarstan, Kazan, Republic of Tatarstan Russia; e-mail: mz.rsloboda_crb@tatar.ru
Adel Yu. Vafin, Cand. Med. Sci., Assistant Professor, Kazan State Medical University, Ministry of Heath of Russia, Kazan, Russia; e-mail: Adel.Vafin@tatar.ru
Irina E. Kravchenko, MD, Assistant Professor; Kazan State Medical University, Ministry of Heath of Russia, Kazan, Russia; e-mail: kravchencoie@mail.ru
Similar Articles