Русский
The level and pattern of healthcare-associated Staphylococcus-induced infections in 2018–2021
DOI: https://dx.doi.org/10.18565/epidem.2023.13.2.28-33
Skachkova T.S., Goloveshkina E.N., Abrosimova O.A., Tutelian A.V., Akimkin V.G.
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
Subjects and methods. For the in-depth epidemiological analysis of the incidence of HCAIs, the analyzed the data of the statistical forms developed by the HCAI Monitoring Reference Center, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, along with data of Section 3 «Nosocomial Infections» of Form 2 the data of the statistical forms developed by the the Reference Center for HCAI Monitoring, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, the Reference Center for HCAI Monitoring, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, which in addition to the data of Section 3 «Nosocomial Infections» of the Federal Statistical Observation «Information on Infectious and Parasitic Diseases». The incidence rates were calculated as the relative frequency of Staphylococcus-induced HCAI cases per 1,000 inpatients. The data on nosocomial bloodstream infections were compared with the open data available on the resource https://amrmap.ru/.
Results. In 2018–2021, there was a downward trend in the incidence of Staphylococcus-induced HCAIs in the Russian Federation. The average long-term rate of decline was 21.2%. During the analyzed period, there were registered 9468 Staphylococcus-induced HCAI cases. The average incidence rate over 4 years was 0.12 per 1,000 inpatients. Surgical site infections occupied the first place in the structure of the forms of methicillin-resistant Staphylococcus HCAIs among the registered cases, outside the pandemic caused by the spread of SARS-CoV-2 coronavirus. In 2020, lower respiratory tract infections held the lead. The official data provided by the territorial bodies of the Federal Service for Supervison of Consumer Rights Protection and Human Well-Being, showed that the absolute number of nosocomial bloodstream infections were lower than their real number in 2018–2020.
Conclusion. Despite the downward trend in the incidence of HCAI caused by Staphylococci, these microorganisms remain in the first place in the etiological structure of HCAIs among the bacterial pathogens. The official data on the incidence may differ significantly from the true number of HCAI cases, which requires regular epidemiological studies and the conditons to be created to optimize the recording of nosocomial infections.
Literature
1. Акимкин В.Г., Тутельян А.В., Брусина Е.Б. Актуальные направления научных исследований в области неспецифической профилактики инфекций, связанных с оказанием медицинской помощи. Эпидемиол. инфекц. болезни. Актуал. вопр. 2014; (2): 40–4. Akimkin V.G., Tutelian A.V., Brusinа E.B. [Recent research directions in the field of nonspecific prevention of infections associated with medical care]. Epidemiоlоgy and infectious diseases. Сurrent items 2014; (2): 40–4. (In Russ.). 2. Зуева Л.П., Любимова А.В. Эпидемиологические проблемы инфекций, связанных с оказанием медицинской помощи, в современный период. Новые горизонты профилактики. Профилактическая и клиническая медицина 2017; 2(63): 7–13. Zueva L.P, Liubimova A.V. [Modern epidemiological problems of healthcare-associated infections. New horizons in prevention]. Preventive and clinical medicine 2017; 2(63): 7–13. (In Russ.). 3. Jia H., Li L., Li W., Hou T., Ma H., Yang Y. et al. Impact of Healthcare-Associated Infections on Length of Stay: A Study in 68 Hospitals in China. BioMed Research International 2019; (1): 1–7. https://doi.org/10.1155/2019/2590563 4. Craft K.M., Nguyen J.M., Berg LJ., Townsend S.D. Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype. Medchemcomm 2019; 10(8): 1231–41. https://doi.org/10.1039/C9MD00044E 5. Ефимова Т.В., Глазовская Л.С., Брусина Е.Б., Дмитренко О.А. Эпидемический процесс инфекций, связанных с оказанием медицинской помощи, вызванных метициллинрезистентными стафилококками: реальность и перспективы. Медицинский альманах 2014; 4(34): 22–7. Efimova T.V., Glazovskaya L.S., Brusina E.B., Dmitrienko O.A. [Epidemic process of infections connected with providing medical assistance caused by methicillin-resistant staphylococci: real state of affairs and prospects]. Medical Almanac 2014; 4(34): 22–7. (In Russ.). 6. Cosgrove S.E., Sakoulas G., Perencevich E.N., Schwaber M.J., Karchmer A.W., Carmeli Ye. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin. Infect. Dis. 2003; 36(1): 53–9. https://doi.org/10.1086/345476 7. Тутельян А.В., Сычева Н.В., Квасова О.А., Орлова О.А., Шулакова Н.И., Голубкова А.А. и др. К вопросу оптимизации системы учета и регистрации ИСМП в России. Сборник тезисов IX Конгресса с международным участием «Контроль и профилактика инфекций, связанных с оказанием медицинской помощи (ИСМП-2021)». М., 2021: 122. Tutelyan A.V., Sycheva N.V., Kvasova O.A., Orlova O.A., Shulakova N.I., Golubkova A.A. et al. [On the issue of optimizing the system of accounting and registration of HAI in Russia. Collection of abstracts of the IX Congress with international participation «Control and prevention of infections associated with the provision of medical care (HAI–2021)». Moscow, 2021: 122. (In Russ.). 8. Ревишвили А.Ш., Оловянный В.Е., Сажин В.П., Анищенко М.М. Хирургическая помощь в Российской Федерации в период пандемии — основные итоги 2020 года. Хирургия. Журнал им. Н.И. Пирогова. 2021; (12): 5–14. https://doi.org/10.17116/hirurgia20211215 Revishvili A.Sh., Olovyannyy V.E., Sazhin V.P., Anishchenko M.M. [Surgical care in the Russian Federation during the pandemic – the main results of 2020]. Pirogov Russian Journal of Surgery 2021; (12): 5–14 https://doi.org/10.17116/hirurgia20211215 (In Russ.). 9. Хирургическая помощь в Российской Федерации. Информационно-аналитический сборник за 2021 год. М., 2022. 200 с. [Surgical care in the Russian Federation. Information and analytical collection for 2021]. M., 2022. 200 p. (In Russ.). 10. Antimicrobial resistance. World Health Organization. 17 November 2021. https://www.who.int/en/news-room/fact-sheets/detail/antimicrobial-resistance 11. Sharov K.S. SARS-CoV-2-related pneumonia cases in pneumonia picture in Russia in March-May 2020; 10(2): 020504. doi: 10.7189/jogh.10.020504 12. World Health Organization. Monitoring and evaluation of the global action plan on antimicrobial resistance: framework and recommended indicators. 2019. https://apps.who.int/iris/handle/10665/325006 13. Скачкова Т.С., Замятин М.Н., Орлова О.А., Юмцунова Н.А., Лашенкова Н.Н., Фомина В.С. и др. Мониторинг метициллинрезистентных штаммов стафилококка в многопрофильном стационаре Москвы с помощью молекулярно-биологических методов. Эпидемиология и Вакцинопрофилактика 2021; 20(1): 44–50. https://doi.org/10.31631/2073-3046-2021-20-1-44-50 Skachkova T.S., Zamyatin M.N., Orlova O.A., Yumtsunova N.A., Lashenkova N.N., Fomina V.S. at al. [Monitoring Methicillin-Resistant Staphylococcus Strains in the Moscow Medical and Surgical Center using Molecular-Biological Methods]. Epidemiology and Vaccinal Prevention 2021; 20(1): 44–50. (In Russ.). https://doi.org/10.31631/2073-3046-2021-20-1-44-50 14. Кузьменков А.Ю., Виноградова А.Г., Трушин И.В., Эйдельштейн М.В., Авраменко А.А., Дехнич А.В. и др. AMRmap – система мониторинга антибиотикорезистентности в России. Клиническая микробиология и антимикробная химиотерапия 2021; 23(2): 198–204. doi: 10.36488/cmac.2021.2.198-204 Kuzmenkov A.Yu., Vinogradova A.G., Trushin I.V., Eidelstein M.V., Avramenko A.A., Dehnich A.V. et al. [AMRmap – a system for monitoring antibiotic resistance in Russia]. Clinical Microbiology and Antimicrobial Chemotherapy 2021; 23(2): 198–204. (In Russ.). doi: 10.36488/cmac.2021.2.198-204
About the Autors
Tatyana S. Skachkova, Researcher, Department of Molecular Diagnostics and Epidemiology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; skachkova@inbox.ru; https://orcid.org/0000-0003-1924-6521
Elena N. Goloveshkina, Сand. Biol. Sci., Head, Laboratory of Molecular Diagnosis and Epidemiology of Infections of Reproduction Organs, Central Research Institute for Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; Moscow, Russia; goloveshkina@cmd.su; https://orcid.org/0000-0002-0536-2874
Olga A. Abrosimova, Head, Epidemiological Service, Epidemiologist, Laboratory of Infections Associated with the Provision of Medical Assistance, Central Research Institute for Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; kvasova@cmd.su; https://orcid.org/0000-0002-4545-1804
Professor Aleksey V. Tutelian, MD; Corresponding Member of the Russian Academy of Sciences; Head, Laboratory of Healthcare-Associated Infections, Central Research Institute for Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; bio-tav@yandex.ru; https://orcid.org/0000-0002-2706-6689
Professor Vasily G. Akimkin, MD, Academicien of the Russian Academy of Sciences, Director, Central Research Institute for Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; vgakimkin@yandex.ru; https://orcid.org/0000-0003-4228-9044.
Similar Articles
