Human immunodeficiency virus-related mortality in the Russian Federation in 1987–2018


DOI: https://dx.doi.org/10.18565/epidem.2020.10.3.54-62

Ladnaia N.N., Pokrovsky V.V., Kozyrina N.V., Sokolova E.V., Dementyeva L.A.

Federal Research and Guidance Center for AIDS Prevention and Control, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
The number of deaths from HIV/AIDS in the world has decreased by 56% versus 2004. This is due to an increase in antiretroviral therapy (ART) coverage and to a decline in the incidence of HIV infection.
Objective. To study trends in HIV -related mortality in the Russian Federation in 1987–2018.
Materials and methods. The paper analyzes personalized data on the number of deaths among HIV-infected patients in the Russian Federation in the period from 1987 to 2018; data of federal state statistical observation forms Nos. 4, 2 and 61; those from the departmental monitoring form of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, and the results of a special study of the causes of death among HIV-infected patients.
Results. In Russia, the HIV infection mortality rate per 100,000 population increased from 0.1 in 2000 to 14.0 in 2018. It was highest among urban male residents (22.8 per 100,000 population in 2018). HIV infection is responsible for premature deaths (the patients die at an average age of 38.9 years); therefore, it has a perceptible impact on demographic processes in the Russian Federation. In this country, 318,870 HIV-infected people (24.0% of the registered patients) died during the entire follow-up period by the end of 2018. In 2018, HIV-related disease is a cause of death in 20,597 Russians, which accounted for more than half of all deaths from infectious diseases. Among the HIV-infected individuals, the total number of deaths from all causes is almost twice as many deaths due to HIV infection; a total of 36,868 patients died in 2018. HIV infection was one of the main causes of premature death in young people, especially in women: in 2018, the HIV-infected people accounted for 21.7% of the women who died at the age of 30–34 years. Among those who died at working age in 2018, HIV infection was a cause of death in 4.9% of the Russians whereas all dead HIV-infected people accounted for even 8.8%. In 2018, the coverage of HIV-infected Russians with ART was low (58.9% of those registered at the dispensary, 42.3% of those living with HIV).
Conclusion. The reasons why HIV mortality rates are higher in the population of the Russian Federation are, with the increasing prevalence of the disease, which is insufficiently limited by preventive measures, a set of factors associated with the shortcomings of the organization of healthcare for HIV-positive citizens, which lead to the incomplete coverage of effective ART among people living with HIV. If the further spread of HIV is not halted and if ART is widely and effectively used, the contribution of HIV infection to premature deaths will constantly increase.

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About the Autors


Natalia N. Ladnaia, Cand. Biol. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: ladnaia@hotmail.com; ORCID: htpp://orcid.org/0000-0003-2994-151X
Prof. Vadim V. Pokrovsky, Academician of the Russian Academy of Sciences, MD, Head, HIV Department, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: pokrovsky.vad@yandex.ru; ORCID: https://orcid.org/0000-0002-9514-7288; Scopus Author ID: 7202457043
Nadezhda V. Kozyrina, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: nad-kozyrina@yandex.ru; ORCID: htpp://orcid.org/0000-0001-5134-0054
Ekaterina V. Sokolova, Cand. Med. Sci., Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; e-mail: ekaterinasokolova007@rambler.ru, ORCID: http://orcid.org/ 0000-0002-2001-8772
Larisa А. Dementyeva, Specialist in Epidemiology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; е-mail: Dementeva_la@gsen.ru


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