Bacterial pneumonias in HIV-infected patients


Puzyryova L.V., Mordyk A.V., Ovsyannikov N.V.

Omsk State Medical University, Ministry of Health of Russia, Omsk, Russia
Community-acquired pneumonia is one of the leading pathologies of respiratory diseases. In connection with the massive consumption of antibacterial drugs, the behavior and landscape of pathogens have significantly changed. With the advent of antiretroviral therapy, the registration rates for opportunistic AIDS-related infections have declined, but the incidence of bacterial pneumonia has not decreased. The common causative agents of community-acquired pneumonia are bacteria, among which Streptococcus pneumonia is a leader. Other microorganisms that cause respiratory infections in HIV-infected patients are S. aureus, H. influenzae, K. pneumoniae, P. aeruginosa, members of the family Enterobacteriaceae, as well as atypical pathogens, such as Legionella pneumophila, Mycoplasma pneumonia, and Chlamydophila pneumoniae, which are found in HIV-positive patients much less frequently than in HIV-negative ones. The HIV-infected patients are very often found to have simultaneously several pathogens of pneumonia, for example, bacteria in combination with viruses, mycobacteria or fungal microflora, which changes the clinical course, radiological parameters and prognosis of the disease.


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About the Autors

Larisa V. Puzyryova, Cand. Med. Sci., Head, Department of Infectious Diseases, Omsk State Medical University, Ministry of Health of Russia, Omsk, Russia; e-mail; ORCID:
Prof. Anna V. Mordyk, MD, Head, Department of Phthisiology and Phthisiosurgery, Omsk State Medical University, Ministry of Health of Russia, Omsk, Russia; e-mail: amordik@ mail. ru; ORCID:
Nikolay V. Ovsyannikov, MD, Associate Professor, Head, Department of Propaedeutics of Internal Diseases, Omsk State Medical University, Ministry of Health of Russia, Omsk, Russia; e-mail:; ORCID:

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