Varicella: clinical presentations, treatment, prevention


Kharchenko G.A., Kimirilova O.G.

Astrakhan State Medical University, Ministry of Health of Russia, Astrakhan, Russia
The current epidemic process is characterized by a rise in varicella incidence among both children and adults, which increases the risk of developing the disease in pregnant women and newborn infants. Polymerase chain reaction and enzyme immunoassay were used to confirm the etiology of varicella in a mother and his baby. There was a clear correlation between the time, at which exanthema appeared in pregnant women, and the severity and outcome of neonatal chickenpox in the newborn. The paper presents the symptomatology of varicella in pregnant women and neonatal chickenpox in relation to the time of fetal infection and to a physician’s policy to treat the mother and child, as well as existing methods to prevent this disease.

Literature


1. Selkova E.P. [Еpidemiology of varicella]. Vaktsinatsiya 2009; (1): 5–7. (In Russ.).

2. Voronin E.M., Ermolenko M.V., Chernova A.M. [Modern features of epidemic process varicella]. Epidemiologiyа i Vaktsinoprofilaktika 2010; 6(55): 17–23. (In Russ.).

3. Harchenko G.A., Zakharov U. [Intrauterine infections in children]. Astrahan: Astrahanskaja gosudarstvennaja medicinskaja akademija Publ.; 2001. 186 р. (In Russ.).

4. Kuskova T.K., Belova E.G., Migmanov T.E. [Chickenpox]. Lechashhij vrach 2004; (1): 33–5. (In Russ.).

5. Lobzin Y.V., Skripchenko E.Y., Karev V.E., Tom A.B. [Congenital varicella: the urgency of the problem and a clinical case]. Rossiyskiy Vestnik Perinatologii i Pediatrii 2012; 57(2): 64–70. (In Russ.).

6. Tatochenko V.K., Ozeretskу N.A., Fedorov A.M. [Chickenpox clinical picture]. Bulletеn vaktsinatsii 2009; (1): 3–9. (In Russ.).

7. Timchenko V.N., Sergeeva S.A., Bulvina O.V. [Treatment and prevention of varicella in children in modern conditions. Guidelines]. Saint-Petersburg; 2008. 32 p. (In Russ.).

8. Kuzmina T.U., Tikhonov U.S., Tikhonov E.P., Babushkina A.O., Andronova N.V. [Features of varicella in adults]. Sibirskoye Meditsinskoye Obozreniye 2013; (2): 72–6. (In Russ.).

9. Lоbzina Y.V., ed. [Chickenpox in modern conditions. Medical manual]. Saint-Peterburg, 2012. 30 р. (In Russ.).

10. Timchenko V. N., Chernova T. M., Drobotenko O. A., Bannova S. P. [Clinical recommendations (treatment protocols) of rendering of medical aid to children suffering from varicella]. Saint-Peterburg, 2015. 45 р. (In Russ.).

11. Vorobeva M.S., Ladyzhenskaya I.P., Barhanova O.A., Varhanova O.A., Ozereckovskij N.A. [A vaccine for the prevention of chickenpox]. Biopreparaty 2010; (1): 32–4. (In Russ.).

12. Vishneva E.A., Namazova- Baranovа L.S. [Chicken pox breakthrough: will change the situation a new scheme of vaccination]. Pediatricheskaya Farmakologiya 2011; 8(6): 20–2. (In Russ.).

13. Vesikari T., Baer G., Willems P. [Immunogenicity and safety of a second dose of measlesmumps–rubella varicella (MMRV) vaccine in healthy children aged 5–6 years]. Pediat. Dis. J. 2007; 26: 153–8.

14. Michalik D.E., Steinberg S.P., La Russa P.S. Primary vaccine failure affer 1 dose of varicella-vaccine in heathy children. J. Infect. Dis. 2008; 197: 944–9.

15. Shapiro E. D., Vargnes M., Esposito D. Effectiveness of 2 doses of varicella vaccine in children. J. Infect. Dis. 2011; 203: 312–5.


About the Autors


For сorrespondence: Gennadij A. Kharchenko, Xarchenkoga@mail.ru


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