Epidemiology and Infectious Diseases » Clinical and pathogenetic aspects of genital herpetic infection

Clinical and pathogenetic aspects of genital herpetic infection

DOI: https://dx.doi.org/10.18565/epidem.2024.14.1.97-101

Pshenichnaya N.Yu., Romanova E.B., Tverdokhlebova T.I., Gopatsa G.V., Suladze A.G.
1) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; 2) M.F. Vladimirsky Moscow Regional Research Clinical Institute Moscow, Russia; 3) Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Rostov-on-Don, Russia; 4) Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia

An analysis of domestic and foreign literature on the prevalence, pathogenesis and features of the clinical course of genital herpes in the modern period is presented. The increasing etiological role of herpes simplex virus type 1 (HSV-1) in this disease has been shown. Data on the great importance of cellular immunity factors in the development of severe forms and relapses of genital herpes are presented. Modern recommendations for the treatment of genital herpes in different categories of patients are discussed.

Keywords: HSV-2, HSV-1, relapse, acyclovir, genital herpes

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About the Autors

Professor Natalia Yu. Pshenichnaya, MD, Deputy Director for Clinical and Analytical Work, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Professor, Department of Infectious Diseases, M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia; pshenichnaya@cmd.su; http://orcid.org/:0000-0003-2570-711X
Elena B. Romanova, MD, Associate Professor, Chief Researcher, Head, Laboratory of Sanitary and Parasitological Monitoring, Medical Parasitology and Immunology, Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Rostov-on-Don, Russia; eromanova1961@yandex.ru; https://orcid.org/0000-0002-6885-6126
Tatiana I. Tverdokhlebova, MD, Director, Rostov Scientific Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Professor, Department of Epidemiology, Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia; rostovniimp@mail.ru; https://orcid.org/0000-0002-3912-0291
Galina V. Gopatsa, Cand. Med. Sci., Senior Researcher, Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; gopatsa@cmd.su; https://orcid.org/0000-0001-8703-7671
Alexander G. Suladze, Cand. Med. Sci., Chief Physician, Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Rostov-on-Don, Russia; ehivrost@mail.ru, http://orcid.org/0000-0002-9051-1220

Clinical and pathogenetic aspects of genital herpetic infection

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About the Autors

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