Русский
Epidemiological and clinical and laboratory features of the new coronavirus infection COVID-19 in children of different age groups in Ryazan
DOI: https://dx.doi.org/10.18565/epidem.2023.13.4.25-31
Belykh N.A., Anikeeva N.A., Akimova E.I., Panferukhina A.Yu., Piznyur I.V., Stezhkina E.V., Sharapina N.M., Privalova N.N., Makarkina E.P., Solovyova O.A.
1) I.P. Pavlov Ryazan State Medical Pavlov, Ryazan, Russia; 2) City Children’s Clinic № 7, Ryazan, Russia; 3) City Children’s Clinic № 6, Ryazan, Russia; 4) City Children’s Clinic № 3, Ryazan Russia
Materials and methods. An analysis of the medical records of 585 patients aged over 1 month up to 17 years of age with a verified diagnosis of new coronavirus infection COVID-19, who were under the follow-up of the local pediatric service of city children’s clinics in Ryazan for the period from March 2020 to December 2021 was carried out.
Results. School-age children accounted for 68.7%. Infection with SARS-CoV-2 in 87.2% of cases occurred as a result of intra-family contact with patients with COVID-19. 71.8% had a mild course of the disease, 5.3% had a moderate course; the diagnosis of «community-acquired pneumonia2» was verified in 4.1% of cases. Premorbid pathology was detected in 8.4% of children; it was 10.7 times more likely to be recorded in children with a moderate course of the disease (p < 0.001). The clinical picture of COVID-19 was dominated by symptoms of intoxication (74.9%) and respiratory tract damage (69.6%). Gastrointestinal manifestations were more common in children aged 0 to 7 years (p < 0.001), dysosmia and dysgeusia – in school-age children (p < 0.001). Asthenic syndrome were noted in 4.7% of children 3 months after new coronavirus infection.
Conclusion. The majority of children had a mild course of coronavirus infection, not requiring hospitalization, with a favorable outcome. Relationships between the severity of coronavirus infection and the presence of concomitant pathology (r = 0.33; p < 0.001), as well as between the age of patients and the presence of gastrointestinal symptoms (r = -0.48; p < 0.001), dysgeusia (r = 0.44; p < 0.001) and dysosmia (r = 0.46; p < 0.001) were established.
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About the Autors
Nataliya A. Belykh, MD, Head, Department of Outpatient Pediatrics with a Course in Pediatrics, Faculty of Additional Professional Education,, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; nbelyh68@mail.ru; htpp://orcid.org/0000-0002-5533-0205
Nataliya A. Anikeeva, Cand. Med. Sci., Assistant Professor, Department of Faculty and Outpatient Pediatrics with a Course in Pediatrics, Faculty of Additional Professional Education, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; natasha782@inbox.ru;htpp://orcid.org/ 0000-0003-1103-2019
Elizaveta I. Akimova, Pediatrician, City Children’s Polyclinic № 7, Ryazan, Russia; elizaveta.akimova.97@mail.ru; htpp://orcid.org/0000-0001-8755-0918
Anastasia Yu. Panferuhina, Resident, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; n.panferuhina@mail.ru; htpp://orcid.org/0000-0002-6926-2418
Inna V. Piznyur, Teaching Assistant, Department of Faculty and Outpatient Pediatrics with a Course in Pediatrics, Faculty of Additional Professional Education, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; innaabramova@yandex.ru; htpp://orcid.org/0000-0002-9267-439X
Elena V. Stezhkina, Cand. Med. Sci., Assistant Professor, Department of Faculty and Outpatient Pediatrics with a Course in Pediatrics, Faculty of Additional Professional Education, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; polus1972@yandex.ru; htpp://orcid.org/0000-0002-1806-0787
Elena P. Makarkina, Deputy Chief Medical Officer, City Children’s Polyclinic № 3, Ryazan, Russia; mak.elena1965@yandex.ru; htpp://orcid.org/0000-0001-6106-6722
Nataliya M. Sharapina, Head, Pediatric Department, City Children’s Polyclinic № 7, Ryazan, Russia; Gdp7@ryazangov.ru
Nataliya N. Privalova, Head, Pediatric Department, City Children’s Polyclinic № 6, Ryazan, Russia; natali-rz@mail.ru
Olga A. Solovyova, Postgraduate Student, Department of Faculty and Polyclinic Pediatrics with a pediatrics course at the Faculty of Continuing Professional Education, I.P. Pavlov Ryazan State Medical University, Ryazan, Russia; olgasolovejka@yandex.ru; htpp://orcid.org/0000-0002-7680-7041
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