Cutaneous leishmaniasis in patients with HIV infection


DOI: https://dx.doi.org/10.18565/epidem.2021.11.3.84-9

Ermak T.N.

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
Cutaneous leishmaniasis is a vector-borne disease that is widespread mainly in endemic regions of the world, which is benign in people with good immunity; however, atypical cases of the disease occur even in endemic regions, whereas immunodeficiency makes its diagnosis difficult. This problem is especially relevant to physicians who work in non-endemic areas, since many of them have poor training in the epidemiology, clinical presentations, and diagnosis of exotic infections. The authors describe their own case of cutaneous leishmaniasis in an HIV-infected patient from the Chechen Republic
Keywords: HV infection, cutaneous leishmaniasis
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Literature

1. Потекаев Н.С., Потекаев Н.Н., Львов А.Н., Пта­шин­ский Р.И., Кочетков М.А., Лебедева Е.В., Маляренко Е.Н., Сапожникова Н.А. Зоонозный кожный лейшманиоз: исторический экскурс и клиническое наблюдение. Клиническая дерматология и венерология 2015; (5): 41–50. doi: 10.17116/klinderma201514541-50

Рotekaev N.S., Potekaev N.N., L’vov A.N., Ptashinskiy R.I., Kochetkov M.A., Lebedeva E.V., Malyarenko E.N., Sapozhnikova N.A. [Zoonotic cutaneous leishmaniasis: historical review and a case study]. Clinical Dermatology and Venereology 2015; (5): 41–50. (In Russ.). doi: 10.17116/klinderma201514541-50


2. Giavedoni P., Iranzo P., Fuertes I., Estrach T., Alsina Gibert M. Cutaneous leishmaniasis: 20 years’ experience in a Spanish Tertiary Care Hospital. Actas Dermosifiliogr 2015; 106(4): 310–316. https://www.ncbi.nlm.nih. gov/pubmed/25678133.


3. Gradoni L., Lopez-Velez R., Mourad M. Manual on case management and surveillance of the leishmaniases in the WHO European region. World Health Organization, 2017. EURO_WHO_Leish_manual_on_case_ management_and_surveillance_9789289052511_2017.pdf


4. Борьба с лейшманиозом Доклад на заседании Комитета экспертов ВОЗ по борьбе с лейшманиозом. Женева, 22–26 марта 2010 г. Серия технических докладов ВОЗ № 949. 225 с. . https://apps.who.int/iris/ handle/10665/89213

[Control of the leishmaniases: report of a meeting of the WHO Expert Commitee on the Control of Leishmaniases], Geneva, 22–26 March 2010. WHO technical report series № 949. 225 р. (In Russ.). https://apps.who. int/iris/ handle/10665/89213


5. Тропическое проклятие. https://medbe.ru/news/meditsina/leyshmanioz-tropicheskoe-proklyatie/

[The Tropical Curse]. https://medbe.ru/news/meditsina/leyshmanioz-tropicheskoe-proklyatie/


6. Alvar J., Aparicio P., Aseffa A., Den Boer M., Cañavate C., Dedet J.P. et al. The relationship between leishmaniasis and AIDS: the second 10 years. Clin Microbiol Rev. 2008; 21(2): 334–59. DOI: 10.1128/CMR.00061-07


7. Ермак Т.Н., Кравченко А.В., Шахгильдян В.И., Понировский Е.Н., Ганкина Н.Ю. Лейшманиоз и ВИЧ-инфекция – актуальная проблема? Журнал инфектологии 2020; (4): 72–77. doi: 10.22625/ 2072-6732-2020-12-4-72-77

Ermak T.N., Kravchenko A.V., Shahgil’dyan V.I., Ponirovsky E.N., Gankina N.Yu. [Leishmaniasis and HIV-infection – an actual problem?]. Journal Infectology 2020, (4), 72–77. (In Russ.). doi: 10.22625/2072-6732-2020-12-4-72-77


8. Ермакова Л.А., Головченко Н.В., Нагорный С.А., Пшеничная Н.Ю., Аванесова Л.А., Журавлев А.С. Аутохтонный случай кожного лейшманиоза у больного ВИЧ-инфекцией. ВИЧ-инфекция и иммуносупрессии 2019; 11(1): 75–80.

Ermakova L.A., Golovchenko N.V., Nagorny S.A., Pshenichnaya N.Yu., Avanesova L.A., Zhuravlev A.S. [Autochthonous сase of cutaneous leishmaniasis in HIV-infected patient]. HIV infection and Immunosuppression 2019; 11(1): 75–80. (In Russ.). doi: http://dx.doi. org/10.22328/2077-9828-2019-11-1-75-80


9. Sánchez Cárdenas C.D., Álvarez Luna Y.J., Bello Hernández Y., Asz Sigall D., Arenas Guzmán R., Sánchez Cárdenas C.D. et al.. Cutaneous Leishmaniasis: A Case Involving the Scalp – Clinical and Videodermoscopic Findings. Skin Appendage Disord. 2018; 4(2): 102–104. doi: 10.1159/00047


10. Савельєв В.Г., Фірюліна О.М., Рябоконь О.В., Зарудна О.В., Добряк Т.Ю., Гостіщева О.І. и др. Випадок завезеного шкірного лейшманіозу в Запоріжжі. Запорізький медичний журнал 2014; 4 (85): 95–98. (In Ukr.). https://doi.org/10.14739/2310-1210.2014.4. 27454


11. Бодня Е.И., Савоськина В.А., Велиева Т.А. Два случая кожного лейшманиоза в Харькове. Дерматология и венерология 2014; (3): 57–63. http://nbuv.gov.ua/UJRN/dtv_2014_3_8

Bodnya E.I., Savoskina V.A., Velieva T.A. [Two cases of skin Leishmaniasis in Kharkiv]. Dermatology and Venereology 2014; (3): 57–63. (In Russ.). http://nbuv.gov.ua/UJRN/dtv_2014_3_8


12. Chiewchanvit S., Tovanabutra N., Jariyapan N., Bates M.D., Mahanupab P., Chuamanochan M.D., Tantiworawit A. et al. Chronic generalized fibrotic skin lesions from disseminated leishmaniasis caused by Leishmania martiniquensis in two patients from northern Thailand infected with HIV. Br. J. Dervmatol. 2015; 663–670. doi.org/10.1111/ bjd.13812


13. Calvopina M., Aguirre C., Cevallos W., Castillo A., Abbasi I., Warburg A. et al. Coinfection of Leishmania guyanensis and Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Ecuador. Am. J. Trop. Med. Hyg. 2017; 96(5): 1151–1154. doi: 10.4269/ajtmh.16-0431


14. Gustavo Henrique Corrêa Soares, Andrea Beatrice Santos da Silva, Lucas Salomão de Sousa Ferreira, Jorim Severino Ithamar, Guilherme de Alencar Medeiros, Silma Regina Ferreira Pereira et al. Case Report: Coinfection by Leishmania amazonensis and HIV in a Brazilian Diffuse Cutaneous Leishmaniasis Patient. Am. J. Trop. Med .Hyg. 2020; 103(3): 1076–1080. doi: 10.4269/ajtmh.20-0131


15. Chaudhary R.G., Bilimoria F.E., Katare S.K.. Diffuse cutaneous leishmaniasis: co-infection with human immunodeficiency virus (HIV). Indian J. Dermatol. Venereol. Leprol. 2008; 74(6): 641–643. DOI: 10.4103/0378-6323.45111


16. Tharakan S.J., Peter C.D., Karthik R., Rupa V., Rose W., Thomas M. et al. Case Report: A Single-Center Case Series on Skin Manifestations of Leishmaniasis from a Non-Endemic State in Southern India. Am. J. Trop. Med. Hyg . 2020; 104(3): 928–933. doi: 10.4269/ajtmh.20-0938


17. Antinori S., Gianelli E., Calattini S., Longhi E., Gramiccia M., Corbellino M. Cutaneous leishmaniasis: an increasing threat for travelers. Clin.Microbiol. Infect. 2005; 11: 343–346. DOI: 10.1111/j.1469-0691.2004.01046.x


18. Рекомендации Европейского клинического общества по борьбе со СПИДом, 2019. http://www.eacsociety.org/fi les/guidelines_10.0-russian.pdf

[Recommendations of the European Clinical Society on AIDS]. 2019. (In Russ.). http://www.eacsociety.org/fi les/guidelines_10.0-russian.pdf


19. Resolution WHA60.13 Control of leishmaniasis (World Health Assembly, 21 May 2007). https://www.who.int/leishmaniasis/resolutions/en/


About the Autors

Tatiana N. Ermak, MD, Leading Research, Central Research Institute of Epidemiology, Federal Center of Hygiene and Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; t.ermak@hiv-russia.ru; http://orcid.org/0000-0001-9490-7129

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