Causes of deaths among persons infected with HIV in the Russian Federation in 2022–2023


DOI: https://dx.doi.org/10.18565/epidem.2025.15.3.6-12

Kravchenko A.V., Ladnaia N.N., Shakhgildyan V.I., Kozyrina N.V., Yurin O.G., Sokolova E.V., Pokrovsky V.V.

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
Objective. Evaluation of the causes of death of patients with HIV infection in the Russian Federation (RF) in 2022–2023.
Materials and methods. An analysis of responses received from 89 regions of the Russian Federation to a special request from the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing on the causes of death of HIV-positive citizens in 2022–2023 was conducted.
Results. In 2022 and 2023, 32,425 and 32,321 deaths were registered among HIV-infected individuals, respectively; of which 1,362 and 1,498 were in the 4 reunited territories, respectively. The proportion of deaths coded by the B20–B24 (HIV infection) code remained unchanged: 41.5% in 2022 and 41.7% in 2023. Mycobacterial infection (B20.0) remained the most common cause of death in the Russian Federation, with a tendency for its proportion to decrease to 27.7% in 2023. Secondary diseases of viral etiology (B20.2 + B20.3), mycoses (B20.4 + B20.5), pneumocystis pneumonia (B20.6), other infectious and parasitic diseases, including cerebral toxoplasmosis (B20.8), led to death in 1.6-4.3% of cases. In 2022 and 2023, the Russian Federation recorded the same proportion of HIV-infected patients (52.2–52.9%), in whom death was caused by diseases not traditionally associated with HIV infection. The most common causes of death were cardiovascular diseases, gastroenterological diseases, injuries, poisoning and some other consequences of exposure to external causes. According to the data received from the 4 territories reunited with the Russian Federation, the etiological cause of death was established only in one third of patients, which is probably due to late detection of HIV infection, late hospitalization in a specialized hospital and initiation of treatment, as well as insufficient diagnostic capabilities of medical institutions and a small proportion of pathomorphological studies. In these territories, the proportion of PLHIV who died due to HIV infection was higher – 56.7 and 56.4%.
Conclusion. In 2022–2023, no significant decrease in the number of HIV-positive citizens who died per year and the proportion of patients among them who died from HIV-related diseases was detected in the territory of the Russian Federation, despite an increase in treatment coverage for patients undergoing follow-up care.
Keywords: new territories of the Russian Federation, fatal outcomes, ART, HIV infection
Read entire article

Literature

1. Покровский В.В., Ладная Н.Н. Вирус иммунодефицита человека в Российской Федерации в 2023 г. Эпидемиол. инфекц. болезни. Актуал. вопр. 2024; 14(3): 21–29. DOI: 10.18565/epidem.2024.14.3.21-9


Pokrovsky V.V., Ladnaya N.N. [Human immunodeficiency virus in the Russian Federation in 2023]. Epidemiоlоgy and infectious diseases. Сurrent items 2024; 14(3): 21–29. (In Russ.). DOI: 10.18565/epidem.2024.14.3.21-9


2. Кравченко А.В., Ладная Н.Н., Козырина Н.В., Покровский В.В., Юрин О.Г., Соколова Е.В. и др. Причины летальных исходов среди лиц, инфицированных ВИЧ, в Российской Федерации в 2008–2018 гг. Эпидемиол. инфекц. болезни. Актуал. вопр. 2020; 10(3): 63–69. DOI: 10.18565/epidem.2020.10.3.63-9


Kravchenko A.V., Ladnaya N.N., Kozyrina N.V., Pokrovsky V.V., Yurin O.G., Sokolova E.V. et al. [Causes of deaths among people infected with HIV in the Russian Federation in 2008–2018]. Epidemiology and infectious diseases. Current items 2020; 10(3): 63–69. (In Russ.). DOI: 10.18565/epidem.2020.10.3.63-9


3. Кравченко А.В., Ладная Н.Н., Покровский В.В., Козырина Н.В., Юрин О.Г., Соколова Е.В. и др. Причины летальных исходов у лиц, инфицированных вирусом иммунодефи­цита человека. Эпидемиол. инфекц. болезни. Актуал. вопр. 2023; 13(3): 56–63. DOI: 10.18565/epidem.2023.13.3.56-63


Kravchenko A.V., Ladnaya N.N., Pokrovsky V.V., Kozyrina N.V., Yurin O.G., Sokolova E.V. et al. [Causes of deaths in persons infected with the human immunodeficiency virus]. Epidemiology and infectious diseases. Current items 2023; 13(3): 56–63. (In Russ.). DOI: 10.18565/epidem.2023.13.3.56-63


4 Кравченко А.В., Ладная Н.Н., Юрин О.Г., Шахгильдян В.И., Соколова Е.В., Козырина Н.В. и др. Оказание медицинской помощи больным ВИЧ-инфекцией в новых регионах Российской Федерации (Донецкая Народная Республика, Луганская Народная Республика, Запорожская область, Херсонская область) в 2022–2023 гг. Материалы науч.-практ. конф. с международным участием «Инфекционные болезни: мультидисциплинарный взгляд». СПб., 2025; 95–99.


Kravchenko A.V., Ladnaya N.N., Yurin O.G., Shakhgildyan V.I., Sokolova E.V., Kozyrina N.V. et al. [Providing medical care to patients with HIV infection in new regions of the Russian Federation (Donetsk People’s Republic, Lugansk People’s Republic, Zaporozhian Region, Kherson Region) in 2022–2023. Materials of the Scientific and Practical Conference with International Participation «Infectious Diseases: A Multidisciplinary Perspective»]. St. Petersburg, 2025; 95–99. (In Russ.).


About the Autors

Рrofessor Alexey V. Kravchenko, МD, Leader Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; alexey-kravtchenko@yandex.ru; http://orcid.org/0000-0001-7857-3763
Natalya N. Ladnaia Cand. Biol. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; n.ladnaya@hiv-russia.ru; http://orcid.org/0000-0003-2994-151X
Vasily I. Shakhgildyan, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; vishakh@yandex.ru; http://orcid.org/0000-0002-8686-0487
Nadezhda V. Kozyrina, Cand. Med. Sci., Senior Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; nad-kozyrina@yandex.ru; http://orcid.org/0000-0001-5134-0054
Oleg G. Yurin, МD, Leading Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; oleg_gerald@mail.ru; htpp://orcid.org/0000-0003-1930-7486
Ekaterina V. Sokolova, Cand. Med. Sci, Researcher, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; ekaterinasokolova007@rambler.ru: http://orcid.org/0000-0002-2001-8772
Рrofessor Vadim V. Pokrovsky, Academician of the Russian Academy of Sciences, MD, Head, Specialized Research Department for the Prevention and Control of AIDS, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; pokrovsky.vad@yandex.ru; http://orcid.org/0000-0002-9514-7288; Scopus Author ID: 7202457043


Similar Articles

Back to Content

Бионика Медиа