The Central Research Institute of Epidemiology has been in the service of diagnosis, therapy, and prevention of acute intestinal infections for 60 years


DOI: https://dx.doi.org/10.18565/epidem.2023.13.2.40-4

Maleev V.V., Gorelov A.V., Ponezheva Zh.B., Tagirova Z.G., Usenko D.V., Grebenkina E.Yu.

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
The overview article presents scientific and practical successes and achievements of the CRIE employees on the topical problems of acute intestinal infections (AIIs). It gives the main stages in the development of diagnosis, in the development of new algorithms for therapy and preventon of AIIs. The classification of dehydration in cholera has been first proposed and introduced into practice and a rationale is given for rehydration therapy for cholera-like diarrhea. Adequate current methods for deciphering the etiological pattern of infectious diarrheas have been developed; the clinical and epidemiological features of intestinal infections; the pathogenesis of diarrhea have been examined, and evidence-based current approaches to diagnosis, differential diagnosis and management tactics in a patient with AIIs.
Keywords: rehydration therapy, acute intestinal infection, diarrhea, differential diagnosis, diagnosis
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About the Autors

Professor Viktor V. Maleev, RAS Full Member, Advisor of the Director for Research, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; maleyev@pcr.ru;; https://orcid.org/0000-0001-5748-178X
Professor Aleksandr V. Gorelov, MD, Academician of the Russian Academy of Sciences, Deputy Director for Scientific Work, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; zdn@pcr.ru; https://orcid.org/0000-0001-9257-0171
Zhanna B. Ponezheva, MD, Leading Researcher, Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; doktorim@mail.ru; https://orcid.org/0000-0002-6539-4878
Zarema G. Tagirova, MD, Leading Researcher, Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; tagirovaz05@mail.ru; ORCID: 0000-0001-6842-908X
Professor Denis V. Usenko, MD, Leading Research Clinical Department of Infectious Pathology; Head, Educational Center, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; dusenko@rambler.ru;  https://orcid.org/0000-0001-5232-7337
Elizaveta Yu. Grebenkina, Laboratory Assistant-Researcher, Clinical Department of Infectious Pathology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; Liza09@mail.ru. https://orcid.org/0000-0001-6567-1401


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