Retrospective analysis of the efficacy of topical and systemic steroids as pathogenetic therapy for viral pneumonias


Koltsova I.V., Fadeeva O.A., Ponezheva Zh.B.

1Infectious Diseases Hospital One, Moscow Healthcare Department, Moscow, Russia; 2A.S. Puchkov Substation Eleven, Ambulance and Emergency Medical Care Station, Moscow, Russia; 3Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
The paper sets forth the present-day views on the pathogenesis of viral pneumonia and acute respiratory distress syndrome. It gives the data of a retrospective analysis of the efficiency of different treatment regimens for patients with acute respiratory viral infection (ARVI) and influenza in the 2009 pandemic period. The paper analyzes the literature sources containing the results of clinical and experimental studies of different treatment regimens for influenza, by analyzing the main mechanisms of action of corticosteroids. It discusses the possibilities, problems, and prospects of different treatment options in patients with the severe course and complications of ARVI/influenza.
Keywords: viral pneumonias, influenza, corticosteroids
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About the Autors

For correspondence:
Irina V. Koltsova, Infectious Disease Physician, Infectious Clinical Hospital One, Moscow Healthcare Department
Address: 63, Volokolamskoye Shosse, Moscow 125367, Russia
Е-mail: Irinfms@mail.ru
Information about the authors:
Olga A. Fadeeva, Infectious Disease Physician, A.S. Puchkov Substation Eleven, Ambulance and Emergency Medical Care Station, Moscow Healthcare Department, 11 substation; Мoscow, Russia; е-mail: fadolga@yandex.ru
Zhanna B. Ponezheva, MD; Leading Researcher, Clinical Department of Infectious Diseases, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Мoscow, Russia; е-mail: doktorim@mail.ru


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